NCT06691230Recruiting
PeRfusiOn Post tHrombEcTomy (PROPHET)
PeRfusiOn Post tHrombEcTomy (PROPHET) A Prospective Observational Cohort Study
Source: ClinicalTrials.gov · Last updated 15 Nov 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Endovascular mechanical thrombectomy is the standard of care for treating patients with a large-vessel occlusion acute ischemic stroke. However, in more than half of these patients, remaining distal vessel occlusions limit the benefit of this therapy. Currently the detection of residual vessel occlusions and the decision for further treatment by the operator is based on the 2D digital subtraction angiography (DSA) images. However, this technique has several limitations. Recently, a new imaging technique, with the possibility to acquire 3D time-resolved perfusion images directly in the operating room was introduced (the flat-panel detector computed tomography perfusion imaging, FDCTP). It can overcome the spatial limitations of 2D DSA, but the details on clinical validation and utility of FDCTP are currently lacking.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 279 (estimated)
- First submitted
- 11 Nov 2024
- Start date
- 1 Nov 2024
- Primary completion date
- 30 Nov 2027
- Lead sponsor
- Insel Gruppe AG, University Hospital Bern
- Diseases
- Stroke
- NCT number
- NCT06691230
What you commit to
- Study type: Observational
- Planned participants: 279
- From 1 Nov 2024 to the primary completion date, 30 Nov 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Inability to follow the clinically indicated visit at 90 days after the index stroke (e.g. patients living abroad).
Other
- Inability to give consent due to insufficient knowledge of the project language
Who the study is looking for
- Informed consent as documented by a signature
- The patients received mechanical thrombectomy or there was the intention to perform endovascular treatment, but only diagnostic angiography was performed.
- Patients received FDCTP as clinically indicated by the treating physician.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospital Basel Coordinator of this site? Confirm its status | Basel | Switzerland | Not yet recruiting |
| University Hospital Bern Coordinator of this site? Confirm its status | Bern | Switzerland | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.