NCT06700005Recruiting
ReadMap: Reading in Stroke Alexia and Typical Aging
Source: ClinicalTrials.gov · Last updated 21 Nov 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Loss of reading ability due to stroke, called alexia, likely affects over a million Americans at any given time and causes difficulty performing many daily life functions, such as paying bills, using email/text, reading for pleasure, and reading signs in the community. Understanding the brain and cognitive basis of alexia could improve diagnosis and treatment of this important problem. In this study, the investigators will perform a large-scale behavioral and brain imaging study of stroke survivors and typical older adults to improve our understanding of the brain and cognitive basis of reading in both of these groups. Participants will complete a battery of tests of reading, speech, language, and thinking abilities. In addition, some participants will complete an MRI. Sessions will be completed across approximately 2-6 weeks, but may be extended depending on participants' schedules and availability. Some participants will be invited to repeat these procedures once or twice in approximately 3-12 months to monitor for changes in reading abilities and MRI measurements over time.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 300 (estimated)
- First submitted
- 6 Nov 2024
- Start date
- 12 Jan 2023
- Primary completion date
- 31 Aug 2028
- Lead sponsor
- Georgetown University
- Diseases
- Stroke
- NCT number
- NCT06700005
What you commit to
- Study type: Observational
- Planned participants: 300
- From 12 Jan 2023 to the primary completion date, 31 Aug 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of other brain disorder that could interfere with our ability to interpret results (e.g., Multiple sclerosis, dementia, head injury causing loss of consciousness)
- Severe psychiatric condition that would interfere with participation in the study
- History of diagnosed learning disorder
Other
- Hearing or vision loss that interferes with performance on behavioral tests even after correction with glasses/hearing aids.
- Inability to follow study procedures despite maximal support
- Additional exclusion criteria for MRIs:
- Presence of metal in the body that is incompatible with MRI
- Pregnancy
- Claustrophobia
Who the study is looking for
- Stroke Survivors:
- Age \>= 18
- Learned English at 8 years or younger
- Brain injury resulting from stroke
- Controls:
- Age \>= 18
- Learned English at 8 years or younger
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Georgetown University Medical Center Coordinator of this site? Confirm its status | Washington D.C. | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.