NCT06701058Completed
Active MMP-8 in Oral Fluid for the Detection of Oral and Oropharyngeal Cancer
Source: ClinicalTrials.gov · Last updated 22 Nov 2024
Brief summary (registry, in English)
The goal of this observational study is to evaluate whether the active-matrix metalloproteinase-8 (aMMP-8) mouth-rinse test can help detect oral and oropharyngeal cancers. Researchers measured aMMP-8 levels in mouth-rinse samples collected from 77 cancer participants and 50 non-cancer participants in a clinical setting. The main question this study seeks to answer: Can the aMMP-8 mouth-rinse test accurately identify and differentiate cancer participants from non-cancer participants in real-time?
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 107 (actual)
- First submitted
- 6 Nov 2024
- Start date
- 28 Mar 2022
- Primary completion date
- 1 Sept 2024
- Lead sponsor
- Helsinki University Central Hospital
- Diseases
- Head and neck cancer, Childhood cancers
- NCT number
- NCT06701058
What you commit to
- Study type: Observational
- Participants enrolled: 107
- From 28 Mar 2022 to the primary completion date, 1 Sept 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Did not follow the manufacturer's instructions prior to the mouth-rinse sample (i.e. brushing teeth before sampling)
Other illness
- In-situ cancer
- Previous cancer diagnosis within five years prior to the examination
Other
- Use of tetracyclines at the time of sampling
Who the study is looking for
- Biopsy-confirmed oral or oropharyngeal cancer identified by the following International Classification of Diseases (ICD-10) codes: C00-C06, C08-C10, C13, and C32 according to the American Joint Committee on Cancer (AJCC) 8th Edition
- Adult
Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Helsinki University Central Hospital Coordinator of this site? Confirm its status | Helsinki | Finland | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.