NCT06702436Completed
Invasive vs. Conservative Management in Cancer Patients With Non-ST Elevation MI (CAN-NSTEMI)"
Impact of Treatment Approaches on Mortality in Cancer Patients With Non-ST Elevation Myocardial Infarction: Invasive vs. Conservative Strategies
Source: ClinicalTrials.gov · Last updated 16 Sept 2025
Brief summary (registry, in English)
This retrospective study investigates the impact of invasive versus conservative management strategies in cancer patients presenting with non-ST elevation myocardial infarction (non-ST MI). Patients aged 18 and older, who were treated for non-ST MI in a hospital setting and had a confirmed cancer diagnosis, are included. The primary outcome is hospital mortality, assessed using GRACE scores to evaluate mortality risk. Patients are grouped based on their received interventions-either invasive (including coronary angiography and revascularization) or pharmacological treatment. Risk factors contributing to mortality, such as cancer type, metastasis presence, comorbidities, and laboratory findings, will also be analyzed to better understand the interplay of oncologic and cardiovascular conditions in this population.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 12500 (actual)
- First submitted
- 19 Nov 2024
- Start date
- 1 Jun 2024
- Primary completion date
- 20 Nov 2024
- Lead sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
- Diseases
- Coronary artery disease
- NCT number
- NCT06702436
What you commit to
- Study type: Observational
- Participants enrolled: 12500
- From 1 Jun 2024 to the primary completion date, 20 Nov 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Incomplete medical records: Patients with missing data on relevant clinical variables (e.g., GRACE score, treatment received, or mortality data).
Other illness
- Non-cancer diagnoses: Patients without a cancer diagnosis.
- ST-Elevation Myocardial Infarction: Patients with ST elevation myocardial infarction (STEMI) instead of non-ST elevation myocardial infarction (NSTEMI).
- Pre-existing severe comorbidities: Patients with severe or terminal comorbidities (e.g., end-stage liver disease, end-stage renal disease, or severe cognitive impairment) that would confound the outcomes.
- Pregnancy: Pregnant patients, as their conditions may complicate the interpretation of results.
Age
- Age: Patients younger than 18 years.
Other
- Inability to provide informed consent: Patients unable to provide informed consent (if applicable).
Who the study is looking for
- Age: Patients aged 18 years and older.
- Diagnosis: Patients with a confirmed cancer diagnosis.
- Acute Condition: Patients diagnosed with non-ST elevation myocardial infarction (non-ST MI).
- Treatment: Patients who received either invasive treatment (including coronary angiography and revascularization) or conservative (pharmacological) treatment for non-ST MI.
- Consent: Patients who have provided informed consent or are part of a retrospective study where consent is waived.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ankara Oncology Training and Research Hospital Coordinator of this site? Confirm its status | Ankara | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.