NCT06703450Enrolling by invitation
Guerbet Liver Fibrosis
Noninvasive Diagnosis of Liver Fibrosis With Gadopiclenol DCE-MRI in Metabolic Dysfunction-associated Steatohepatitis (MASH)
Source: ClinicalTrials.gov · Last updated 21 Apr 2026
Brief summary (registry, in English)
The goal of this study is to assess the value of liver dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and texture analysis post gadopiclenol for liver fibrosis staging, in comparison with MR elastography, T1 mapping, ultrasound elastography and blood tests in 50 initial patients with metabolic dysfunction-associated steatohepatitis (MASH).
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 50 (estimated)
- First submitted
- 21 Nov 2024
- Start date
- 28 Feb 2024
- Primary completion date
- 1 Oct 2026
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Diseases
- Fatty liver disease (MASLD/MASH)
- NCT number
- NCT06703450
What you commit to
- Study type: Observational
- Planned participants: 50
- From 28 Feb 2024 to the primary completion date, 1 Oct 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous history or current diagnosis of HCC or decompensation.
Age
- Contraindications for MRI, including
- Medically unstable
- Intracranial clips
- Metal implants
- Suspected or confirmed metal in eyes
- Cardiac pacemaker, implanted defibrillator, other implanted electronic device
- Pregnancy: Pregnancy tests will be offered to women of childbearing age at no cost
- Severe claustrophobia
Who the study is looking for
- Patients with suspected MASLD (F0-F4) with clinically indicated percutaneous or transjugular liver biopsy within 6 months of MRI (before or after MRI).
- Both genders.
- Age \> 18 years.
- Any racial/ethnic background.
Age in the registry: 18 years to 89 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mount Sinai Coordinator of this site? Confirm its status | New York | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.