NCT06703736Recruiting
Functional and Morphological Characterization of Multiple Osteochondromas Disorder
Misure di funzionalità e deformità Dell'Apparato Muscolo-scheletrico Come "Biomarkers" Per il Trattamento di Malattie Ortopediche/Accessible Measurements of Mobility and Deformity as Biomarkers for Orthopaedic Treatments
Source: ClinicalTrials.gov · Last updated 24 Mar 2026
Brief summary (registry, in English)
The main purpose of the study is the characterization of functional and morphological alterations due to multiple osteochondromas in a pediatric and adult population through the identification of relevant anthropometric and functional parameters. The morphological and functional data, supplemented with clinical and postural data, will allow the characterization of the disease with an holistic approach that can provide important information to properly assess timing for surgical treatments and to improve the quality of life of these patients. Another goal of the study is the assessment and the validation of novel instruments and tools to measure joint mobility and bone deformity. These instruments should be easy-to-use and designed to be operated locally by the patients themselves and/or in small clinics by operators with little training and no specific high-technical knowledge. The final goal of the study is the assessment of the quality of life and balance perception of patients, using questionnaires.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 60 (estimated)
- First submitted
- 22 Oct 2024
- Start date
- 21 May 2025
- Primary completion date
- 1 Sept 2026
- Lead sponsor
- Istituto Ortopedico Rizzoli
- NCT number
- NCT06703736
What you commit to
- Study type: Observational
- Planned participants: 60
- From 21 May 2025 to the primary completion date, 1 Sept 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Persons who do not fit the inclusion criteria;
- Any reason which, in the opinion of the investigator, would result in the inability of the participant to comply with the protocol.
- BMI equal to or greater than 30.
Who the study is looking for
- For multiple osteochondromas cohort inclusion criteria are:
- clinical and/or molecular diagnosis of Multiple Osteochondromas;
- male and female subjects;
- age minors: 6-17 years at enrollment and adult age: 18-40 years at enrollment;
- collection of appropriate informed consent;
- ability to walk a linear path without aids;
- presence of multiple osteochondromas localized at lower limbs;
- ability to undergo all procedures required by the protocol.
- For healthy cohort inclusion criteria are:
- absence of neuro-muskuloskeletal or other limb-limiting conditions in the lower limbs;
- male and female subjects;
- age minors: 6-17 years at enrollment and adult age: 18-40 years at enrollment;
- collection of appropriate informed consent;
- ability to undergo all procedures required by the protocol.
Age in the registry: 6 years to 40 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| IRCCS Istituto ortopedico Rizzoli Coordinator of this site? Confirm its status | Bologna | Italy | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.