NCT06706323Recruiting
Depressive Symptoms After Cardiac Surgery
Predictive Modelling of Clinically Significant Depressive Symptoms After Coronary Artery Bypass Graft Surgery
Source: ClinicalTrials.gov · Last updated 1 Apr 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The primary goal of this project is to develop a predictive model for clinically significant depressive symptoms (CSDS) in patients undergoing coronary artery bypass graft (CABG) surgery, using pre- and perioperative data. CSDS occur in about 30 percent of CABG patients, which is four times higher than in the general population. These symptoms are linked to poor quality of life and increased morbidity and mortality. The aim is to create a model that can identify patients at risk for postoperative depression. This tool could help clinicians make informed decisions and take preventive measures to manage depression after surgery.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 300 (estimated)
- First submitted
- 22 Nov 2024
- Start date
- 25 Nov 2024
- Primary completion date
- 1 Apr 2027
- Lead sponsor
- Roland von Känel
- Diseases
- Coronary artery disease
- NCT number
- NCT06706323
What you commit to
- Study type: Observational
- Planned participants: 300
- From 25 Nov 2024 to the primary completion date, 1 Apr 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Cognitive impairment according to a score of ≤ 7 (maximum score = 9) on a modified version of a short version of the Mini-Mental State Examination and the Brief Interview for Mental Status
- Any serious comorbid non-cardiac medical condition likely to cause death within 1 year (e.g. metastatic cancer)
Other
- Active psychotic symptoms (assessed with two items from the Youth Psychosis At Risk Questionnaire), substance abuse and/or dependence within the past 6 months (assessed with a single-item questionnaire), and/or active suicidal ideations (assessed with a single item from the M.I.N.I.).
- Acute or emergency CABG
Who the study is looking for
- Elective Off-Pump CABG or CABG, either isolated or combined with valve intervention
- Men and women, aged between 18 and 90 years
- Sufficient knowledge of German language in reading and understanding
- Oral and Signed consent form
- Ability and Willingness to follow the study protocol
Age in the registry: 18 years to 90 years · Sex: All
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Stadtspital Zürich (City Hospital Zurich) Triemli Coordinator of this site? Confirm its status | Zurich | Switzerland | Recruiting |
| University Hospital Zurich (USZ) Coordinator of this site? Confirm its status | Zurich | Switzerland | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.