NCT06707519Recruiting
NSCLC Liquid Biopsies and Exhaled VOC
A Prospective, Single Center Study to Test the Validity and Feasibility of Circulating Tumor DNA in Blood, Sputum and Alveolar Fluid, as Well as Exhaled Volatile Organic Compounds as Biomarkers in Non-Small Cell Lung Cancer
Source: ClinicalTrials.gov · Last updated 22 Apr 2026
Brief summary (registry, in English)
The objective of the study is to determine the feasibility of recruiting participants and using sputum, Bronchoalveolar lavage (BAL) and exhaled Volatile Organic Compounds (VOC) in addition to blood, as biological samples for detecting mutations in extracted cell-free DNA in non-small cell lung cancer (NSCLC) patients, before and after surgery, and any recurrence within a 24-month postoperative follow-up period. This is a pilot feasibility study, proposed as a 24-month prospective, single-center, non-interventional, observational trial with NSCLC-adenocarcinoma patients indicated for resection surgery with curative intent.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 210 (estimated)
- First submitted
- 25 Nov 2024
- Start date
- 1 Feb 2023
- Primary completion date
- 29 Dec 2027
- Lead sponsor
- St. Joseph's Healthcare Hamilton
- Diseases
- Lung cancer
- NCT number
- NCT06707519
What you commit to
- Study type: Observational
- Planned participants: 210
- From 1 Feb 2023 to the primary completion date, 29 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with previously treated malignancy less than 5 years prior to current resection (not including skin cancer).
Other illness
- Resection done with non-curative intent or metastatic disease
- other malignancies
Who the study is looking for
- Patient must be at least 18 years of age
- Patient must be able to provide consent
- Patients undergoing surgical resection with curative intent for non-small cell lung cancer at St. Joseph's Healthcare Hamilton and Firestone Institute for Respiratory Health.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| St. Joseph's Healthcare Hamilton Coordinator of this site? Confirm its status | Hamilton | Canada | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.