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NCT06720922Recruiting

MRgLITT for mTLE: A PROBE Trial

Magnetic Resonance-guided Laser Interstitial Thermal Therapy for Mesial Temporal Lobe Epilepsy: A Prospective, Randomized, Open Blinded, End-point Trial

Source: ClinicalTrials.gov · Last updated 21 Jan 2026

Brief summary (registry, in English)

How does magnetic resonance-guided laser interstitial thermal therapy (MRgLITT) impact clinical prognosis in mesial temporal lobe epilepsy (mTLE)?

Status (registry)
Recruiting
Study type
Interventional
Enrollment
120 (estimated)
First submitted
3 Dec 2024
Start date
21 Jul 2025
Primary completion date
1 Jan 2027
Lead sponsor
Beijing Tiantan Hospital
Diseases
Epilepsy
NCT number
NCT06720922

What you commit to

  • Study type: Interventional
  • Planned participants: 120
  • From 21 Jul 2025 to the primary completion date, 1 Jan 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • History of brain surgery.
  • Individuals with significant medical comorbidities or conditions that pose an excessive risk for surgery, such as severe cardiovascular disease, respiratory disorders, or uncontrolled systemic infections.

Other

  • Intracranial space occupying lesions.

Who the study is looking for

  • 18-65 years.
  • Drug-resistant mesial temporal lobe epilepsy.
  • Seizure frequency ≥ 1 time /month.
  • Participants approved.

Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Beijing Tiantan Hospital
Coordinator of this site? Confirm its status
BeijingChinaRecruiting

Related publications

This page is information, not medical advice. Discuss any trial with your doctor.