NCT06721416Completed
Comparing the Acute Effects of Different Exercise Approaches in Patients With Multiple Sclerosis
Comparing the Acute Effects and Cortical Hemodynamic Response of Different Exercise Approaches in Patients With Multiple Sclerosis: fNIRS Study
Source: ClinicalTrials.gov · Last updated 17 Sept 2025
Brief summary (registry, in English)
Multiple Sclerosis (MS) is the second most common neurological disorder in young adults after trauma. Treatments developed today can slow progression and reduce symptoms. Exercise therapy is a useful rehabilitation practice in MS to manage symptoms, restore function, optimize quality of life, ensure well-being and increase participation in daily life activities. In this study, it is planned to investigate the acute effects of conservative and virtual reality (VR)-based aerobic exercise applications and standard exercises that frequently form the rehabilitation programs of individuals with MS in clinics. For this purpose, patients with MS who met the inclusion criteria were given two-week intervals; Conservative aerobic exercise, virtual reality-based aerobic exercise and standard exercise practices will be performed. With the data obtained from this study, it is aimed to investigate the safety of aerobic exercises performed using VR tools that can be used in telerehabilitation applications, which are thought to have a very important place in MS rehabilitation in the future, in terms of acute body temperature increase, cognitive and physical fatigue caused by conservative methods and fNIRS cortical effects of VR-based aerobic exercise applications. It will be possible to prove it with objective methods such as.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 12 (actual)
- First submitted
- 3 Dec 2024
- Start date
- 1 Dec 2024
- Primary completion date
- 30 Jul 2025
- Lead sponsor
- Acibadem University
- Diseases
- Multiple sclerosis
- NCT number
- NCT06721416
What you commit to
- Study type: Interventional
- Participants enrolled: 12
- From 1 Dec 2024 to the primary completion date, 30 Jul 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Having previous full immersive VR experience.
- Continuing the active physical therapy and rehabilitation program.
Other illness
- Having an additional neurological disease.
Other
- Spasticity in any muscle of the upper extremity \> 3, according to MAS.
Who the study is looking for
- Diagnosed as Relapsing Remitting MS by neurologist according to the McDonald Criteria.
- 18-55 years old.
- EDSS score \< 4.5
- Mini mental examination test score ≥ 24
- No MS attack in the last 6 months.
- No visual or vestibular deficits.
- Signed the written consent form.
Age in the registry: 18 years to 55 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Acibadem University Coordinator of this site? Confirm its status | Ataşehir | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.