NCT06724029Recruiting
Neurosurgical Outcome Network
Neurosurgical Outcome Network Per la Predizione Dell'Outcome in Neurochirurgia
Source: ClinicalTrials.gov · Last updated 30 Mar 2026
Brief summary (registry, in English)
The evaluation of neurosurgical outcomes varies from center to center, and the predictive factors that determine these outcomes are not fully known or shared. This study aims to assess outcomes and their predictors using measures agreed upon by the participating centers. Standardizing the evaluation of outcomes and predictors improves the quality of research, allows for data comparison, and facilitates a "common language" in routine clinical practice. Most importantly, it influences therapeutic decisions in various neurosurgical conditions. Clinically, the identified predictors can also be used during preoperative assessments to provide more precise guidance to patients undergoing surgery.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 4500 (estimated)
- First submitted
- 2 Dec 2024
- Start date
- 5 Dec 2022
- Primary completion date
- Jun 2027
- Lead sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
- Diseases
- Epilepsy, Parkinson disease
- NCT number
- NCT06724029
What you commit to
- Study type: Observational
- Planned participants: 4500
- From 5 Dec 2022 to the primary completion date, Jun 2027
- 27 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- For cognitive and psychological assessment: patients with psychiatric diseases in history and/or taking psychotropic drugs; presence of overt cognitive decline (not due to the injury) in history; patients younger than 18 years old.
Who the study is looking for
- Neuro-oncological pathology: supratentorial and subtentorial tumors, intra and extra axial tumors excluding the skull base (anterior, middle and posterior fossa; sellar and parasellar region)
- Basicranial pathology: tumors originating from the anterior cranial fossa, middle cranial fossa and posterior cranial fossa, sellar region with or without supratentorial/parasellar development.
- Vascular pathology: aneurysms, AVMs, cavernomas, other pathologies (Moyamoya disease, dural fistulas, nontraumatic hematomas)
- Traumatic pathology: diffuse damage (nonvisible diffuse damage, diffuse damage, diffuse damage with edema, diffuse damage with shift) and focal damage (acute/subacute/chronic subdural hematoma, extradural hematoma, subarachnoid hemorrhage, intraparenchymal hematoma, fractures); hydrocephalus. The inclusion criterion for chronic subdural hematoma is recent bleeding for TBI with CT finding of chronic subdural hematoma candidate for evacuation surgery.
- Spinal pathology: degenerative cervical (anterior/posterior), myelopathic, and trauma pathology; instrumented, uninstrumented thoracolumbar pathology (disc pathology, canal pathology), and trauma pathology; oncologic spinal pathology.
- Functional pathology: Parkinson's disease, spasticity, trigeminal neuralgia, craniofacial pain/algia, neuropathic pain, tremor, dystonias, obsessive compulsive disorder, drug-resistant epilepsies, depression. Normotensive hydrocephalus.
- Peripheral nervous system pathology: peripheral nerve compression syndromes, peripheral nerve and plexus tumors, brachial plexus and peripheral nerve trauma (contusion and section)
- Malformative pathology: Chiari malformation type 1 and craniostenoses including both those framed in malformative syndromes and those not framed in malformative syndromes (monosutural craniostenoses: trigonocephaly, plagiocephaly, scaphocephaly; multisutural craniostenoses). Malformative hydrocephalus.
- For cognitive and psychological assessment: age 18 years or older; adequate understanding of Italian language; diagnosis of glioma, meningioma, vascular pathology, spinal pathology
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (27)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| 1. ASST Papa Giovanni XXIII Coordinator of this site? Confirm its status | Bergamo | Italy | Active, not recruiting |
| Spedali Civili Brescia Coordinator of this site? Confirm its status | Brescia | Italy | Active, not recruiting |
| Fondazione Poliambulanza Istituto Ospedaliero Coordinator of this site? Confirm its status | Brescia | Italy | Active, not recruiting |
| Azienda Ospedaliero Universitaria Policlinico "G. Rodolico - San Marco" Coordinator of this site? Confirm its status | Catania | Italy | Recruiting |
| ASST Lariana, Ospedale S. Anna Coordinator of this site? Confirm its status | Como | Italy | Active, not recruiting |
| ASST Cremona Coordinator of this site? Confirm its status | Cremona | Italy | Active, not recruiting |
| Azienda Ospedaliero-Universitaria Careggi Coordinator of this site? Confirm its status | Florence | Italy | Recruiting |
| Ospedale F. Spaziani di Frosinone Coordinator of this site? Confirm its status | Frosinone | Italy | Recruiting |
| Ospedale Moriggia Pelascini Coordinator of this site? Confirm its status | Gravedona | Italy | Active, not recruiting |
| Ospedale Alessandro Manzoni Coordinator of this site? Confirm its status | Lecco | Italy | Active, not recruiting |
| ASST Ovest Milanese Coordinator of this site? Confirm its status | Legnano | Italy | Active, not recruiting |
| Ospedali Riuniti di Livorno -Azienda USL Toscana nord ovest Coordinator of this site? Confirm its status | Livorno | Italy | Recruiting |
| Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico Coordinator of this site? Confirm its status | Milan | Italy | Active, not recruiting |
| Fondazione IRCCS Istituto Neurologico Carlo Besta Coordinator of this site? Confirm its status | Milan | Italy | Recruiting |
| Istituto Clinico Città Studi Coordinator of this site? Confirm its status | Milan | Italy | Active, not recruiting |
| Asst Santi Paolo E Carlo Coordinator of this site? Confirm its status | Milan | Italy | Recruiting |
| ASST Fatebenefratelli Sacco Coordinator of this site? Confirm its status | Milan | Italy | Active, not recruiting |
| Policlinico di Monza Coordinator of this site? Confirm its status | Monza | Italy | Recruiting |
| Fondazione IRCCS San Gerardo dei Tintori Coordinator of this site? Confirm its status | Monza | Italy | Active, not recruiting |
| A.R.N.A.S. Ospedali Civico di Palermo Coordinator of this site? Confirm its status | Palermo | Italy | Recruiting |
| Azienda Ospedaliero Universitaria di Parma Coordinator of this site? Confirm its status | Parma | Italy | Active, not recruiting |
| Fondazione IRCCS Policlinico San Matteo Coordinator of this site? Confirm its status | Pavia | Italy | Active, not recruiting |
| ASL Roma 1 Coordinator of this site? Confirm its status | Roma | Italy | Recruiting |
| Fondazione Policlinico Universitario Gemelli di Roma Coordinator of this site? Confirm its status | Roma | Italy | Recruiting |
| IRCCS Istituto Clinico Humanitas Coordinator of this site? Confirm its status | Rozzano | Italy | Active, not recruiting |
| ASST della Valtellina ed Alto Lario Coordinator of this site? Confirm its status | Sondrio | Italy | Active, not recruiting |
| Azienda Sanitaria Universitaria Friuli Centrale di Udine Coordinator of this site? Confirm its status | Udine | Italy | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.