NCT06724172Recruiting
CHIME: Comparing Health Interventions for Maternal Equity
Source: ClinicalTrials.gov · Last updated 5 Mar 2026
Brief summary (registry, in English)
The goal of this comparative effectiveness trial is to compare how three different approaches to overcome barriers to resources and provide nutrition and physical activity counseling improve maternal healthy weight in pregnancy and postpartum. The main question it aims to answer is which of the two multi-level, multi-component interventions has greater effectiveness in reducing maternal postpartum weight retention at 12-months postpartum. Hypothesis (primary): Both multi-level, multi-component interventions will have greater effectiveness reducing maternal postpartum weight retention at 12-months postpartum than the usual care group. Hypothesis (secondary): The community-based intervention will have greater effectiveness than the self-management intervention. Participants will be asked to participate in one of the study interventions from early pregnancy until 12 months postpartum and complete five research visits. General procedures include completion of: * Questionnaires * Dietary recalls * In-depth interviews * Anthropometric measurements * Collection of blood via finger stick or blood panel
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 795 (estimated)
- First submitted
- 4 Dec 2024
- Start date
- 22 Jan 2026
- Primary completion date
- 15 Jan 2030
- Lead sponsor
- Stanford University
- Diseases
- Obesity
- NCT number
- NCT06724172
What you commit to
- Study type: Interventional
- Planned participants: 795
- From 22 Jan 2026 to the primary completion date, 15 Jan 2030
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Underlying disease/treatment that might impact weight status (e.g., significant gastrointestinal conditions, major psychiatric disorders, and others at the discretion of the study clinician)
Age
- Age \< 18 years at baseline because of unique developmental differences of adolescents and regulations regarding age of consent
Other
- Underweight (BMI \<18 kg/m2) at pre-pregnancy period
- Unwillingness or inability to complete study visits or intervention components
- Unwillingness or inability to commit to intervention components for self or infant, including plans to move more than 100-mile radius from recruitment site
- Multiple gestations
Who the study is looking for
- Maternal age 18 years or older
- Maternal gestational age ≤ 20 weeks with viable singleton pregnancy documented on first trimester ultrasound with an intention to continue pregnancy to term
- Plans to continue receiving antenatal care at the recruitment site/network
- Maternal characteristics include at least one of the following:
- Self identifies as Black/African American
- Self identifies as Hispanic/Latino/a/e/x
- Insured by Medicaid
- Maternal ability to speak English or Spanish
- Completion of baseline data collection (maternal survey data, weight, and height measurement prior to randomization)
Age in the registry: 18 years to - · Sex: Female · Accepts healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| New York Presbyterian Queens Coordinator of this site? Confirm its status | Flushing | United States | Recruiting |
| Columbia University Medical Center Coordinator of this site? Confirm its status | New York | United States | Recruiting |
| NYU Langone Health Coordinator of this site? Confirm its status | New York | United States | Recruiting |
| Stanford University Coordinator of this site? Confirm its status | Palo Alto | United States | Active, not recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.