NCT06725004CompletedPhase 3
Oxytocin Versus Human Chorionic Gonadotropin as Trigger in Ovulation Induction
Oxytocin Versus Human Chorionic Gonadotropin as Trigger in Ovulation Induction Cycles: A Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 29 Aug 2025
Brief summary (registry, in English)
The goal of this clinical trial is to learn if injection oxytocin can be used as trigger in ovulation induction cycles in infertile women with polycystic ovary syndrome. The main questions it aims to answer are: * Does injection oxytocin have similar ovulation rate as injection human chorionic gonadotropin (hCG) when used as trigger? * Does injection oxytocin have similar pregnancy rate as injection human chorionic gonadotropin (hCG) when used as trigger? Researchers will compare injection oxytocin to injection hCG to see if injection oxytocin is as effective as injection hCG as trigger in ovulation induction cycles in infertile women with polycystic ovary syndrome. Participants will * Take injection oxytocin or injection hCG as trigger over three subsequent ovulation induction cycles * Be checked for ovulation by follicular rupture in TVS after 36 hours or raised serum progesterone level on day 7 after trigger * Be checked for pregnancy by urine pregnancy test kit after missed period
- Status (registry)
- Completed
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 60 (actual)
- First submitted
- 5 Dec 2024
- Start date
- 1 Jan 2023
- Primary completion date
- 31 Dec 2023
- Lead sponsor
- Shakeela Ishrat
- NCT number
- NCT06725004
What you commit to
- Study type: Interventional · Phase 3
- Participants enrolled: 60
- From 1 Jan 2023 to the primary completion date, 31 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Any drugs that affect the functions of hypothalamus, pituitary gland, and gonads
Other illness
- Any pelvic pathology like pelvic inflammatory diseases
- Any cardiovascular diseases or other systemic diseases
- Any known hypersensitivity to oxytocin
Other
- Male factor abnormality
- Bilateral tubal block
- Any uterine abnormality
- Ovarian cysts
- Hyperprolactinemia or thyroid dysfunction
Who the study is looking for
- Infertile women with polycystic ovary syndrome
- Age less than 40 years
- Had ovulation induction with letrozole, with at least one mature follicle detected on folliculometry
Age in the registry: 20 years to 40 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Bangabandhu Sheikh Mujib Medical University Coordinator of this site? Confirm its status | Dhaka | Bangladesh | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.