NCT06725927Active, not recruitingPhase 4
Vaccination Against Influenza Pre-discharge in Heart Failure
Vaccination Against Influenza Pre-discharge in Patients Hospitalized Due to Heart Failure
Source: ClinicalTrials.gov · Last updated 23 Jul 2025
Brief summary (registry, in English)
In patients with heart failure (HF), influenza vaccination should be considered to prevent HF hospitalizations. However, vaccination rates among patients with HF are low, in part because of subjective but common concerns about whether patients with such severe disease should be vaccinated. In this randomized, open-label study, we will investigate whether influenza vaccination before discharge in patients stabilized after cardiac decompensation is safe and improves outcomes over a 6-month follow-up period.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 200 (estimated)
- First submitted
- 5 Dec 2024
- Start date
- 31 Dec 2024
- Primary completion date
- 30 Nov 2025
- Lead sponsor
- Wroclaw Medical University
- Diseases
- Heart failure
- NCT number
- NCT06725927
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 200
- From 31 Dec 2024 to the primary completion date, 30 Nov 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- severe post-vaccination reaction during influenza vaccination in any previous influenza season
- antibiotic therapy among the drugs recommended for taking after hospitalization.
Other illness
- hypersensitivity to any of the components of the vaccine planned to be administered
Other
- discharge to another hospital for continued treatment or discharge to a nursing home
Who the study is looking for
- informed consent to participate in the study
- hospitalization (unplanned) due to exacerbation (decompensation) of heart failure
- planned discharge within the next 48 hours due to completion of hospital treatment
- no current (2024/25 season) influenza vaccination.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Jan Mikulicz Radecki University Hospital in Wroclaw Coordinator of this site? Confirm its status | Wroclaw | Poland | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.