NCT06727214Active, not recruiting
Survival Benefits of Neoadjuvant Systemic Chemotherapy in Muscle Invasive Bladder Cancer
Survival Benefit of Neoadjuvant Systemic Chemotherapy in Muscle Invasive Bladder Cancer and Factors Affecting Its Response - Retrospective Study
Source: ClinicalTrials.gov · Last updated 3 Nov 2026
Brief summary (registry, in English)
Muscle-invasive bladder cancer (MIBC) is an aggressive disease with a high-risk of early metastasis and cancer specific mortality. The gold standard treatment of MIBC is radical cystectomy (RC) in conjunction with concomitant bilateral pelvic lymphadenectomy . While radical cystectomy remains a primary management strategy for MIBC, high rates of recurrence with surgery alone highlight the likelihood of occult micrometastatic disease at the time of diagnosis. Due to the development and implementation of neoadjuvant chemotherapy prior to radical cystectomy, the prognosis for MIBC patients undergoing radical cystectomy has improved .
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 87 (estimated)
- First submitted
- 3 Dec 2024
- Start date
- 4 Nov 2025
- Primary completion date
- 4 Nov 2026
- Lead sponsor
- Sara Mahmoud Ahmed Mahmoud
- Diseases
- Bladder cancer
- NCT number
- NCT06727214
What you commit to
- Study type: Observational
- Planned participants: 87
- From 4 Nov 2025 to the primary completion date, 4 Nov 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients treated with surgery firstly
Other illness
- Non muscle invasive bladder cancer (NMIBC)
Other
- Metastatic patients
Who the study is looking for
- Age \>18
- histological proven MIBC patient treated with neoadjuvant systemic chemotherapy( platinum based )
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Assuit universty hospitals Coordinator of this site? Confirm its status | Asyut | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.