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NCT06727825Completed

Evaluation of Grass Pollen Sensitization Among Professionals Exposed or Not Exposed to Flour

Source: ClinicalTrials.gov · Last updated 15 Dec 2025

Brief summary (registry, in English)

Occupational asthma are a major etiology of allergic asthma, especially among manual labor. The baker job exposes to significant level of flour. Some of allergenic components at work have simitudes with environmental allergens, for example cereals flour with gramineous pollens. GRAMIPRO is a retrospective cohort study that analyzes data from one specialized center at Créteil in the Paris region. The primary goal is to assess Participants include women and men aged over 18 years old at the time of their first consultation in the Occupational and Environmental Pathology Department of Créteil between April 2011 and July 2023, in order to explore asthma from an allergological perspective, patients working as bakers, pastry chefs, or restaurant workers, who are aware of exposed and patients in other professions; asthmatic patients with or without associated rhinitis. Exclusions apply for patients who opposing to participate, patients without asthma symptoms; and patients who did not consult for the first time in the given period. Data will be stored, anonymized, and analyzed using EasyMedStat. Data collection is scheduled between January 1 and 31, 2025 This research aims to o explore the factors that may influence the occurrence and severity of flour-induced allergic asthma symptoms in professionals exposed to this allergen, in order to consider prevention strategies and tools to advise individuals pursuing careers that expose them to flour. This study is intended for allergists, occupational physicians, general practitioners, and pulmonologists.

Status (registry)
Completed
Study type
Observational
Enrollment
403 (actual)
First submitted
6 Dec 2024
Start date
2 Jan 2025
Primary completion date
28 Mar 2025
Lead sponsor
Centre Hospitalier Intercommunal Creteil
Diseases
Asthma
NCT number
NCT06727825

What you commit to

  • Study type: Observational
  • Participants enrolled: 403
  • From 2 Jan 2025 to the primary completion date, 28 Mar 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • patients who opposing to participate in study
  • patients without asthma symptoms
  • patients who did not consult for the first time in the given period.
  • Patient without occupational activity the day of the first consult or in the past

Who the study is looking for

  • patients who consulted between April 2011 and July 2023 for an occupational asthma
  • active subjects
  • Over 18 years at the first consultation with no upper limit
  • Having not expressed their opposition to participate in the study

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
Centre Hospitalier Intercommunal de Créteil
Coordinator of this site? Confirm its status
CréteilFranceUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.