NCT06731998Recruiting
Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery
Evaluating Optimal Perioperative Pain Management: A Prospective Randomized Control Trial of Laparoscopic Transversus Abdominis Plane Block With Local Anesthetic, Laparoscopic Transversus Abdominis Plane Block Alone, and Local Anesthetic Alone in Minimally Invasive Oncologic Surgery
Source: ClinicalTrials.gov · Last updated 18 Sept 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This is a research study to evaluate the effectiveness of 3 different types of routine pain management regimens used during clinically indicated, minimally invasive oncologic (cancer) surgery. This project is considered "Research" and participation is voluntary. Upon enrollment in this study, the research team will collect data from the patient's medical records. The patient will undergo all of the normal testing and procedures required pre-operatively (standard of care). The study team will then randomly assign the patient (like a flip of a coin) to one of three different study arms for pain management during surgery: 1. Laparoscopic Transversus Abdominis Plane Block (LapTAP) with Local Anesthetic (LA) 2. Laparoscopic Transversus Abdominis Plane Block (LapTAP) only 3. Local Anesthetic (LA) only The patient will receive standard pre- and post-operative care according to clinical guidelines (routine care). The study team will collect information from the patient's medical record for the first 24 hours after their surgery and upon discharge. This information will include pain scores, amount of medication required, any side effects the patient may have experienced, and satisfaction with pain control. Participation in the study will end upon discharge from the hospital.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 48 (estimated)
- First submitted
- 12 Nov 2024
- Start date
- 5 Feb 2025
- Primary completion date
- 30 Jun 2026
- Lead sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
- NCT number
- NCT06731998
What you commit to
- Study type: Interventional
- Planned participants: 48
- From 5 Feb 2025 to the primary completion date, 30 Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients who have undergone major surgery within the last 6 months.
Other illness
- Patients with chronic pain disorders or on long-term opioid or analgesic therapy.
- Patients with known contraindications to the study drugs or procedures (e.g., allergy to LA or contraindications to LapTAP).
- Patients with cognitive impairments or psychiatric conditions that could interfere with pain assessment or understanding of informed consent.
Age
- Patients age less than 18 or ≥ 90
Other
- Pre-existing hepatic dysfunction, cirrhosis
- Patients with an ASA classification of IV or higher.
- Patients unable to understand the language in which consent and study-related information are provided (The study and the study-related information will be in the English Language)..
- Female patients who are pregnant.
- Patients currently enrolled in another clinical trial that might interfere with the outcome measures of this study.
Who the study is looking for
- Male and female patients age ≥ 18 - 89
- Patients scheduled for elective (clinically indicated) hepatic, gastric, biliary, pancreatic, gynecologic, colorectal, other GI Minimally invasive oncologic surgery.
- Patients who have provided informed consent to participate in the study.
- Patients with an American Society of Anesthesiologists (ASA) physical status classification of I, II, or III.
- Patients undergoing procedures anticipated to last more than 1 hour but less than 8 hours.
- Patients able to understand and self-report pain using the designated pain Visual Analog Scale
Age in the registry: 18 years to 89 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| AHN West Penn Hospital Coordinator of this site? Confirm its status | Pittsburgh | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.