NCT06733389Not yet recruiting
Peripheral Venous Pressure Variation, Pulse Pressure Variation and Pleth Variability Index for Fluid Responsiveness
Comparison of Peripheral Venous Pressure Variation, Pulse Pressure Variation and Pleth Variability Index in Predicting Fluid Responsiveness
Source: ClinicalTrials.gov · Last updated 17 Dec 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Pulse pressure variation (PPV) and pleth variability index (PVI) are widely used in clinical practice as indicators of the responsiveness to fluid therapy in patients receiving mechanical ventilation. PPV, which measures changes in arterial pressure, requires arterial puncture, which is invasive, and PVI, which detects subtle changes in oxygen saturation, requires an expensive, commercial monitoring equipment. In this study, we aimed to measure peripheral venous pressure variation using less invasive waveform variation in peripheral veins and to determine whether this indicator can be clinically used to predict the responsiveness to fluid therapy. In addition, the investigators aimed to confirm the superiority of the indicators by comparing them with the responsiveness to fluid therapy of the PPV and PVI.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 150 (estimated)
- First submitted
- 10 Dec 2024
- Start date
- 28 Dec 2024
- Primary completion date
- 28 Nov 2025
- Lead sponsor
- Seoul National University Bundang Hospital
- Diseases
- Stroke
- NCT number
- NCT06733389
What you commit to
- Study type: Observational
- Planned participants: 150
- From 28 Dec 2024 to the primary completion date, 28 Nov 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with abnormal findings on electrocardiogram before surgery
Other
- Patients who cannot undergo peripheral venous puncture
Who the study is looking for
- Patients voluntarily agreed and signed the written informed consent form before participating in the study
- Adults aged 19 years or older
- American Society of Anesthesiologists physical class (ASA) 1-3
- Patients scheduled for elective hepatectomy under general anesthesia
- Patients who require arterial pressure monitoring and additional peripheral venous access for routine anesthesia preparation
- Non-smokers with normal pulmonary function
Age in the registry: 19 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Seoul National University Bundang Hospital Coordinator of this site? Confirm its status | Seongnam-si | South Korea | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.