NCT06734273Active, not recruitingEarly phase 1
Randomized Control Trial of Sleeve Gastrectomy With Tirzepatide in Maximizing Weight Loss
Source: ClinicalTrials.gov · Last updated 21 Sept 2026
Brief summary (registry, in English)
This study examines whether adding tirzepatide-a medication that helps with weight loss-after sleeve gastrectomy surgery can help people lose more weight after the surgery; better improve conditions like Type 2 diabetes, high blood pressure, high cholesterol, and sleep apnea after surgery and; whether this causes more complications or side effects compared to surgery alone.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Early phase 1
- Study type
- Interventional
- Enrollment
- 42 (estimated)
- First submitted
- 9 Dec 2024
- Start date
- 10 Mar 2025
- Primary completion date
- Sept 2027
- Lead sponsor
- Nicholas Skertich
- Diseases
- Obesity
- NCT number
- NCT06734273
What you commit to
- Study type: Interventional · Early phase 1
- Planned participants: 42
- From 10 Mar 2025 to the primary completion date, Sept 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior metabolic and bariatric surgery
- Prior use of GLP-1 agonist
- Prior history of pancreatitis
Other illness
- Personal/family history of medullary thyroid cancer or MEN type 2
- Any eating disorder
- History of acute coronary syndrome or myocardial infarction
- History of stroke
- Active malignancy
- History of diabetic retinopathy
- History of gastroparesis
Lab values
- Hepatic dysfunction: AST/ALT \>3 ULN
- Renal dysfunction eGFR\<45ml/min/1.73m2
Other
- Secondary cause of obesity
- Pregnancy/lactation
Who the study is looking for
- Adult 18 to 65 years of age
- Body Mass Index \>35 with comorbidity of Type 2 Diabetes and/or Hypertension and/or Hyperlipidemia and/or Obstructive Sleep Apnea OR Body Mass Index \>40 with or without comorbidity
- Undergoing primary sleeve gastrectomy
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Rush University Medical Center Coordinator of this site? Confirm its status | Chicago | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.