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NCT06737029Completed

Alternative Diagnoses in Patients About to Start Empiric Tuberculosis Treatment

Enhanced Diagnostic Workup for Patients About to Start Empiric Tuberculosis Treatment in Lusaka, Zambia

Source: ClinicalTrials.gov · Last updated 25 Aug 2026

Brief summary (registry, in English)

This study is being conducted to determine whether in patients who are diagnosed with tuberculosis on a clinical basis (where tuberculosis is not found in the sputum) might have other lung diseases than tuberculosis. Depending on the precise nature of your complaints, additional investigations shall be requested by the study investigators. Possible additional investigations will include laboratory tests on samples of your blood, an additional chest X-ray, lung function testing (where you will have to blow air into a machine, so that your lung capacity is registered), CT-scan, and bronchoscopy. The information obtained through the investigations done in this study will help in the management of your illness and other patients who are diagnosed with tuberculosis on a clinical basis.

Status (registry)
Completed
Study type
Observational
Enrollment
311 (actual)
First submitted
8 Dec 2024
Start date
1 Dec 2024
Primary completion date
10 Aug 2026
Lead sponsor
Stichting Longartsen voor Afrika
Diseases
Tuberculosis
NCT number
NCT06737029

What you commit to

  • Study type: Observational
  • Participants enrolled: 311
  • From 1 Dec 2024 to the primary completion date, 10 Aug 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • suspected drug-resistant tuberculosis
  • inpatient (because of suspected tuberculosis)

Other

  • unable to visit central study site for review or additional investigations

Who the study is looking for

  • adult patient
  • about to start TB treatment for suspected pulmonary tuberculosis, but with sputum GeneXpert negative

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University Teaching Hospital
Coordinator of this site? Confirm its status
LusakaZambiaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.