NCT06737614Recruiting
Relationship Between Pulse Pressure and Stroke Volume in the Critically Ill Patients: The ANDROMEDA-PEGASUS Study
Can Pulse Pressure Assessment at the Bedside Detect Low Values or Track Changes of Stroke Volume in Critically Ill Patients? The Multicenter, Cross-sectional, Observational, ANDROMEDA-PEGASUS Study
Source: ClinicalTrials.gov · Last updated 29 May 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The goal of this study is to assess the predictive capacity of pulse pressure to estimate stroke volume, as assessed by bedside echocardiography in critically ill patients. We hypothesize that pulse pressure will be able to adequately detect low values of stroke volume, and to track changes of stroke volume during commonly used dynamic cardiovascular interventions. Pulse pressure transduced from an arterial line will be measured simultaneously with left ventricular outflow tract velocity time integral in a broad range of critically ill patients. Ancillary clinical, hemodynamic and echocardiographic data will also be registered.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 1500 (estimated)
- First submitted
- 12 Dec 2024
- Start date
- 1 May 2025
- Primary completion date
- 30 Oct 2025
- Lead sponsor
- Pontificia Universidad Catolica de Chile
- Diseases
- Stroke
- NCT number
- NCT06737614
What you commit to
- Study type: Observational
- Planned participants: 1500
- From 1 May 2025 to the primary completion date, 30 Oct 2025
- 3 sites in 3 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Pregnancy
- Inadequate arterial line transduction (see below)
- Refusal of consent
- Patient who requires extracorporeal circulation
Who the study is looking for
- 18 years
- Admitted to ICU
- Functioning arterial line in place
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital Do Coracao Coordinator of this site? Confirm its status | São Paulo | Brazil | Recruiting |
| Hospital Clinico UC Christus Coordinator of this site? Confirm its status | Santiago | Chile | Recruiting |
| Fundación Valle del Lili Coordinator of this site? Confirm its status | Cali | Colombia | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.