NCT06738043Not yet recruiting
Dexmedetomidine Versus Ketamine as Adjuvants in Bariatric Surgery
Dexmedetomidine Infusion Versus Low Dose Ketamine Infusion as an Adjuvant in Bariatric Surgery: A Randomized Controlled Comparative Study
Source: ClinicalTrials.gov · Last updated 9 Apr 2026
Brief summary (registry, in English)
This randomized controlled trial aims to compare the analgesic efficacy of dexmedetomidine infusion versus low-dose ketamine infusion as adjuvants in bariatric surgery. The study includes 90 patients undergoing bariatric surgery at Menoufia University Hospital, randomized into three groups: dexmedetomidine, ketamine, and control (placebo). Primary outcomes include total morphine consumption intra- and post-operatively. Secondary outcomes include postoperative pain scores, total analgesic consumption, time to first analgesic request, hemodynamic parameters, and patient satisfaction. This study seeks to explore safer, more effective pain management strategies to minimize opioid use in bariatric surgery patients.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 90 (estimated)
- First submitted
- 12 Dec 2024
- Start date
- 20 Apr 2026
- Primary completion date
- 20 Apr 2027
- Lead sponsor
- Tanta University
- Diseases
- Obesity
- NCT number
- NCT06738043
What you commit to
- Study type: Interventional
- Planned participants: 90
- From 20 Apr 2026 to the primary completion date, 20 Apr 2027
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of hypersensitivity to dexmedetomidine or ketamine.
- History of substance abuse or chronic opioid use.
- Severe hepatic or renal impairment.
- Cardiopulmonary disorders.
- Severe diabetes mellitus.
- Psychiatric disorders, seizures, uncontrolled hypertension (systolic ≥ 140 mmHg or diastolic ≥ 90 mmHg), or heart block.
Other
- American Society of Anesthesiologists (ASA) physical status III or IV.
Who the study is looking for
- Patients aged 18-60 years.
- Both sexes.
- Body mass index (BMI) > 35 kg/m², scheduled for bariatric surgery.
- American Society of Anesthesiologists (ASA) physical status I-II.
Age in the registry: 18 years to 60 years · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.