NCT06740864Completed
40 Hz Transcranial Alternating Current Stimulation for Inducing Gamma Oscillations
Induction and Stabilization of Gamma Oscillations With 40 Hz Transcranial Alternating Current Stimulation in Healthy Elderly
Source: ClinicalTrials.gov · Last updated 18 Mar 2026
Brief summary (registry, in English)
This study aims to compare the efficacy of different 40 Hz tACS protocols in entraining gamma oscillations, which are linked to various cognitive functions and play a significant role in cognitive impairments like Alzheimer's disease. Specifically, it examines the effects of 40 Hz tACS applied to frontal brain regions versus fronto-temporal regions on gamma oscillations and working memory in healthy elderly individuals.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 30 (actual)
- First submitted
- 14 Dec 2024
- Start date
- 1 Jun 2024
- Primary completion date
- 1 Feb 2025
- Lead sponsor
- The National Brain Mapping Laboratory (NBML)
- Diseases
- Alzheimer disease
- NCT number
- NCT06740864
What you commit to
- Study type: Interventional
- Participants enrolled: 30
- From 1 Jun 2024 to the primary completion date, 1 Feb 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Taking CNS, blood pressure and other medications
- having metal implants in the head and neck
Other illness
- history of neurological or psychiatric disorders including seizures or epilepsy,
Other
- significant cognitive decline meassured by The Montreal Cognitive Assessment (MoCA)
Who the study is looking for
- healthy elderly between 50-80 years of age
- normal or corrected to normal eye vision
- right-handed
- non-smokers
- at least 70 % accuracy in working memory training task
Age in the registry: 50 years to 85 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Institute for Research in Fundamental Sciences Coordinator of this site? Confirm its status | Tehran | Iran | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.