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NCT06743490Recruiting

Capturing Key MG-symptoms Using Smartphone Recordings.

Capturing Key Symptoms Using Smartphone Recordings in Patients With Myasthenia Gravis (CAPTURE-MG)

Source: ClinicalTrials.gov · Last updated 8 Jul 2026

Brief summary (registry, in English)

This study will make use of a cross-sectional design of MG patients and non-MG participants to quantitatively assess key MG symptoms, and to explore the applicability of machine learning algorithms to their measurement.

Status (registry)
Recruiting
Study type
Observational
Enrollment
225 (estimated)
First submitted
9 Dec 2024
Start date
18 Mar 2025
Primary completion date
28 Aug 2026
Lead sponsor
Leiden University Medical Center
NCT number
NCT06743490

What you commit to

  • Study type: Observational
  • Planned participants: 225
  • From 18 Mar 2025 to the primary completion date, 28 Aug 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Subjects currently taking part in a clinical trial of an Investigational Medicinal Product.
  • Subjects who have used an immediate release pyridostigmine-based medication in the 12 hours prior to their participation and participants on prolonged release pyridostigmine.

Other illness

  • Subjects with a diagnosed neurological disease resulting in muscle weakness, other than MG.
  • 1\. Limitation of upper limb mobility or speech impairment of any cause.

Other

  • Not willing to be audio-recorded for the study assessments.
  • Not willing to be video-recorded for the study assessments.
  • Subjects have cognitive or physical limitations that, in the opinion of the investigator, limits the subject's ability to complete study procedures/
  • Subjects with an upper-limb amputation or who are non-verbal.

Who the study is looking for

  • Age ≥ 18 years
  • Ability to understand the requirements of the study and provide written informed consent.
  • A clinical diagnosis of myasthenia gravis (ocular or generalized) as defined by the Dutch national guideline (category "definite" or "probable" MG).
  • MGFA Clinical Classification of disease severity I-IV.
  • Subjects have at least one of the symptoms of interest (namely dysarthria, dysphonia, proximal arm fatigue and/or ptosis).
  • Subjects are not diagnosed with and have no clinical suspicion of MG.
  • Subjects do not have a medical history of any of the symptoms of interest (namely dysarthria, dysphonia, proximal arm fatigue and/or ptosis).

Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
Leiden University Medical Center
Coordinator of this site? Confirm its status
LeidenNetherlandsNot yet recruiting

This page is information, not medical advice. Discuss any trial with your doctor.