NCT06746428Active, not recruiting
Activity Coaching During Pelvic Radiation Therapy
ACTIVATE: A Pilot Randomized Activity Coaching Trial to Increase Vitality and Energy During Post-operative Pelvic Radiation Therapy for Endometrial Cancer
Source: ClinicalTrials.gov · Last updated 1 Sept 2026
Brief summary (registry, in English)
Research has shown that for women who are undergoing pelvic radiation therapy, fatigue is a common side effect. Fatigue that occurs during radiation therapy can make it harder to perform daily living activities. While there are studies that recommend exercise as a treatment for fatigue in cancer patients and survivors, there are currently no studies that focus on the role of exercise for women undergoing pelvic radiation therapy. The purpose of this study is to see if incorporating an activity coaching program is helpful in improving treatment-related fatigue for women undergoing pelvic radiation therapy for endometrial cancer.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 16 (estimated)
- First submitted
- 17 Dec 2024
- Start date
- 27 Jan 2025
- Primary completion date
- 1 Mar 2027
- Lead sponsor
- Inova Health Care Services
- Diseases
- Endometrial cancer
- NCT number
- NCT06746428
What you commit to
- Study type: Interventional
- Planned participants: 16
- From 27 Jan 2025 to the primary completion date, 1 Mar 2027
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Medical comorbidities including:
- Unstable angina
- Uncontrolled dysrhythmias
- Acute pulmonary embolus
- Active pulmonary infection
Other
- Unable to schedule and attend coaching visits
- Participation in a regular exercise program of ≥150 minutes of moderate intensity exercise a week at baseline
- Unable to perform the five-times stand test
Who the study is looking for
- At least 18 years of age
- Pathologic diagnosis of endometrial cancer (any histology, Stage I-IVA)
- Has undergone modified radical or radical hysterectomy
- Plan to receive adjuvant treatment with pelvic external beam radiation therapy at ISCI
- ECOG performance status of 0-1
- Patient has a computer, smart phone, or tablet virtual access to the web-based platform and email
- Able to read, understand and provide written informed consent
- Deemed appropriate for unmonitored exercise by treating physician based on the following evidence-based criteria (1)
- Walk without any assistance or assistance device
- Absence of significant cognitive impairment
- Absence of high risk for falls
- Participant does not need to refrain from any activity
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Inova Schar Cancer Institute - Alexandria Coordinator of this site? Confirm its status | Alexandria | United States | Unknown status |
| Inova Schar Cancer Institute Coordinator of this site? Confirm its status | Fairfax | United States | Unknown status |
| Inova Schar Cancer Institute - Fair Oaks Coordinator of this site? Confirm its status | Fairfax | United States | Unknown status |
| Inova Schar Cancer Institute - Loudoun Coordinator of this site? Confirm its status | Leesburg | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.