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NCT06749262Recruiting

Inclined Versus Standard Exercise for COPD Patients

Inducing Variable Breathing Ratios During Walking to Improve Exercise Capacity in Patients With Chronic Obstructive Pulmonary Disease.

Source: ClinicalTrials.gov · Last updated 13 Apr 2026

Brief summary (registry, in English)

This study is designed to provide information regarding how to improve pulmonary rehabilitation for persons with chronic obstructive pulmonary disease (COPD). Pulmonary rehabilitation is an exercise program for COPD patients that is recommended and benefits some, but not all, patients. The question being studied in this trial is whether during an exercise program, walking on an incline might be better than walking on faster on a flat surface in training muscles so that patients might be less short of breath with exercise.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
54 (estimated)
First submitted
19 Dec 2024
Start date
1 Apr 2026
Primary completion date
1 Sept 2029
Lead sponsor
VA Office of Research and Development
Diseases
COPD
NCT number
NCT06749262

What you commit to

  • Study type: Interventional
  • Planned participants: 54
  • From 1 Apr 2026 to the primary completion date, 1 Sept 2029
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Subjects taking medications that alter mood or metabolic demand will be excluded

Other illness

  • Confounding effects such as neurological, musculoskeletal, or metabolic disease

Other

  • All potential subjects must be cleared for participation by a physician after undergoing a cardiopulmonary exercise test
  • Require an O2 mask during rest or activity

Who the study is looking for

  • Veterans from all sex/gender, race, and ethnicity will be recruited
  • All subjects will undergo post-bronchodilator spirometry and be clinically stable
  • All subjects must have documented FEV1/FVC ratio of \<0.7, and between 30% to 80% FEV1% predicted
  • If subjects have non-qualifying spirometry, they will not be screened further
  • Subjects with qualifying spirometry will be screened further
  • Potential subjects must have a BMI of less than 35 kg/m2 and must be free from co-morbidities that may affect walking patterns
    • e.g., peripheral arterial disease, diabetes, low back pain

Age in the registry: 45 years to 80 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Omaha VA Nebraska-Western Iowa Health Care System, Omaha, NE
Coordinator of this site? Confirm its status
OmahaUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.