NCT06750497Recruiting
Forearm Immobilization in T2D
The Impact of Short-term Forearm Immobilization on Forearm Muscle Glucose and Amino Acid Metabolism of Volunteers With or Without Type 2 Diabetes
Source: ClinicalTrials.gov · Last updated 2 Jul 2026
Brief summary (registry, in English)
The aim of the present study is to assess the impact of short-term forearm immobilization on forearm muscle glucose uptake and amino acid net balance and kinetics in individuals with T2D compared with a control group with normoglycaemia.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 26 (estimated)
- First submitted
- 22 Nov 2024
- Start date
- 21 Nov 2024
- Primary completion date
- 30 Apr 2027
- Lead sponsor
- Wageningen University
- Diseases
- Type 2 diabetes
- NCT number
- NCT06750497
What you commit to
- Study type: Interventional
- Planned participants: 26
- From 21 Nov 2024 to the primary completion date, 30 Apr 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Chronic use of any prescribed or over-the-counter pharmaceuticals (excluding oral contraceptives and contraceptive devices) that interact with muscle substrate metabolism (e.g. selective serotonin reuptake inhibitors)
- Any previous motor disorders or inborn errors in muscle and/or lipid metabolism
Other illness
- Type 1 or a genetic form of diabetes
- Any diagnosed cardiovascular (heart) disease or high blood pressure (≥160 mmHg systolic and/or ≥100 mmHg diastolic)
- A personal or family history of thrombosis (clots)
- History of kidney disease
- History of liver disease
- History of any drug or alcohol abuse in the past two years
Other
- Consumption of a low-carbohydrate diet
- Smoking or chewing tobacco
- Known anaemia
- Regular use of dietary protein and/or amino acid supplements (\>3 times per week)
- Currently involved in a structured progressive resistance training program (\>3 times per week)
- Pregnant or breastfeeding
- Claustrophobia
- Unable to give consent
Who the study is looking for
- Males and females with or without diagnosed type 2 diabetes
- Use lifestyle changes, metformin, gliclazide, or a combination thereof as oral glucose-lowering treatments for T2D
- Aged 18-80 years at the time of signing informed consent
- 18.5 ≥ BMI ≤ 35 kg·m2
Age in the registry: 18 years to 80 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Wageningen University and Research Coordinator of this site? Confirm its status | Wageningen | Netherlands | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.