NCT06757010CompletedPhase 2
A Study of NE3107 in Early Parkinson's
A Double-Blind, Randomized, Placebo-controlled, Study of NE3107 in Subjects With Early Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 11 Aug 2026
Brief summary (registry, in English)
The goal of this clinical trial is to learn if bezisterim can treat movement symptoms of Parkinson's disease in patients that are 45 to 80 years old, in generally good physical and mental health, and are nearing the need for treatment to relieve their symptoms but have not yet been prescribed any form of levodopa or drug with similar activity. The main questions it aims to answer are: * Will bezisterim decrease movement symptoms of Parkinson's disease? * What medical problems do participants have when taking bezisterim? Researchers will compare the effects of bezisterim treatment to placebo (a look-alike substance that contains no drug) to see if bezisterim works to treat movement symptoms of Parkinson's disease. Participants will * have a physical examination that includes an electrocardiogram * take drug or placebo twice daily for four months * visit a clinical site or receive an at home visit seven times over the course of five months
- Status (registry)
- Completed
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 57 (actual)
- First submitted
- 24 Dec 2024
- Start date
- 26 Mar 2025
- Primary completion date
- 1 May 2026
- Lead sponsor
- BioVie Inc.
- Diseases
- Parkinson disease
- NCT number
- NCT06757010
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 57
- From 26 Mar 2025 to the primary completion date, 1 May 2026
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- has taken levodopa or another similar drug for the motor symptoms of PD
Other illness
- major mental health or physical illness
- medical history of major mental or physical illness
Other
- a known or strongly suspected familial cause for PD diagnosis
Who the study is looking for
- 45 years to 80 years of age
- diagnosed with idiopathic Parkinson's Disease (PD) within 18 months
- nearing the need for symptomatic therapy
- agree to use birth control measures
- provide voluntary consent
- willing to allow blood collection for DNA methylation analysis
- pass all screening tests and procedures
Age in the registry: 45 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Dent Neurologic Coordinator of this site? Confirm its status | Amherst | United States | Unknown status |
| NeuroScience Research Center LLC Coordinator of this site? Confirm its status | Canton | United States | Unknown status |
| QUEST Research Institute Coordinator of this site? Confirm its status | Farmington Hills | United States | Unknown status |
| Science 37 (Nationwide Site) Coordinator of this site? Confirm its status | Morrisville | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.