NCT06757530Completed
Radiomics Model for Assessing Lymph Node Status in cN0 Patients withHNSCC
CT-based Radiomics Predicts Occult LNM and Uncovers Immune Microenvironment of Head and Neck Cancer
Source: ClinicalTrials.gov · Last updated 28 May 2025
Brief summary (registry, in English)
Occult lymph node metastasis (LNM) remains one of the most critical and challenging aspects of managing head and neck squamous cell carcinoma (HNSCC). Defined as the presence of metastatic disease in lymph nodes that are clinically undetectable through routine imaging or physical examination, occult LNM has profound implications for treatment planning, prognosis, and overall patient management. In HNSCC, accurate detection and prediction of occult LNM are crucial as they significantly influence decisions regarding the extent of neck dissection, the need for adjuvant therapies, and the overall therapeutic strategy. Undiagnosed or underestimated LNM can result in inadequate treatment, increasing the risk of locoregional recurrence and poor survival outcomes.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 700 (actual)
- First submitted
- 27 Dec 2024
- Start date
- 27 Nov 2024
- Primary completion date
- 15 Apr 2025
- Lead sponsor
- First Affiliated Hospital of Chongqing Medical University
- Diseases
- Head and neck cancer
- NCT number
- NCT06757530
What you commit to
- Study type: Observational
- Participants enrolled: 700
- From 27 Nov 2024 to the primary completion date, 15 Apr 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients who received other treatments before surgery;
Other
- CT images with significant artifacts;
- Patients with tumor recurrence.
Who the study is looking for
- Availability of complete clinical data;
- Diagnosis of laryngeal squamous cell carcinoma confirmed by surgery or biopsy;
- CT contrast-enhanced examination performed within two weeks prior to surgery.
- All patients underwent neck lymph node dissection surgery.
Age in the registry: 18 years to 89 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The First Affiliated Hospital of Chongqing Medical University Coordinator of this site? Confirm its status | Chongqing | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.