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NCT06764277Completed

Mechanisms and Phenotypes of Hypertension in Patients in Chronic Hemodialysis

Source: ClinicalTrials.gov · Last updated 3 Feb 2026

Brief summary (registry, in English)

The goal of this study is to evaluate interdialytic blood pressure changes of the patients in chronic hemodialysis. The main question to be answered is: What is the relative importance of weight gain, the renin angiotensin system, the sympathetic nervous system and inflammatory immune reactivity in the interdialytic hypertension of patients in chronic hemodialysis, The participants will have hemodynamic evaluation (cardiac output and peripheral vascular resistance) at the end of dialysis, ambulatory monitoring of blood pressure in the interdialytic period. Serum samples will be collected at the end of dialysis and before the start of the next dialysis, 2-3 days later.

Status (registry)
Completed
Study type
Observational
Enrollment
32 (actual)
First submitted
19 Dec 2024
Start date
14 Aug 2023
Primary completion date
20 Dec 2024
Lead sponsor
Bernardo Rodríguez Iturbe
NCT number
NCT06764277

What you commit to

  • Study type: Observational
  • Participants enrolled: 32
  • From 14 Aug 2023 to the primary completion date, 20 Dec 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Prior nephrectomy

Other illness

  • Patients with active infection

Other

  • Patients unable to give informed consent or withdrawal of informed consent to the study
  • Patients with prosthesis or pacemakers
  • Patients with immunosuppressive treatment of more than 10mg Prednisone daily
  • incomplete collection of data specified in the study protocol

Who the study is looking for

  • Patients with more than 3 months in the chronic hemodialysis program in the INCMNSZ and assumed to remained in the program for longer than 3 months
  • Stable patients with no change in medication 1 month prior to the study
  • Unchanged drug therapy and dialysis prescription for \>1 month prior to the studies
  • Informed consent to participate in the study

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
Coordinator of this site? Confirm its status
Mexico CityMexicoUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.