NCT06765252Recruiting
Effect of Genetic Polymorphism on Capecitabine-Induced Toxicity in Egyptian Cancer Patients
Source: ClinicalTrials.gov · Last updated 9 Jan 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The goal of this observational study is to study the effect of a single nucleotide polymorphism in the CES1 gene (rs2244613) on capecitabine-induced toxicity in Egyptian cancer patients. This study will help in understanding the interindividual variability in the CES1 gene and the effect of a single nucleotide polymorphism in this gene (rs2244613) on capecitabine-induced toxicity in participants already taking capecitabine-based chemotherapy as part of their regular medical care.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 80 (estimated)
- First submitted
- 12 Nov 2024
- Start date
- 1 Apr 2024
- Primary completion date
- Apr 2025
- Lead sponsor
- Ain Shams University
- Diseases
- Colorectal cancer
- NCT number
- NCT06765252
What you commit to
- Study type: Observational
- Planned participants: 80
- From 1 Apr 2024 to the primary completion date, Apr 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients treated with irinotecan
- Patients having inability to take oral medication
Other illness
- Patients with malabsorption syndrome
- Patients with chronic diarrhea as ulcerative colitis or Crohn's disease
Other
- Lack of physical integrity of the upper gastrointestinal tract
- Patients with poor performance status
Who the study is looking for
- Patients with breast or colorectal cancer receiving capecitabine-based chemotherapy
- Age \> 18 years
- ECOG PS 0-2.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Clinical Oncology, Faculty of Medicine, Menoufia University Coordinator of this site? Confirm its status | Shibīn al Kawm | Egypt | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.