NCT06765642Recruiting
The Effect of Non-invasive Brain Stimulation rTMS on Hand Muscles in Chronic Stroke Patients.
Evaluation of 3 Patterned rTMS Stimulation Dosage on Corticospinal Excitability and Motor Learning in Stroke Patients
Source: ClinicalTrials.gov · Last updated 22 May 2026
Brief summary (registry, in English)
The study is about using a brain stimulation technique called rTMS (Repetitive Transcranial Magnetic Stimulation) to help improve hand muscles in people who had a stroke. Researchers want to understand how this device can help stroke patients use their hands better.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 26 (estimated)
- First submitted
- 17 Dec 2024
- Start date
- 9 Jun 2025
- Primary completion date
- 13 Apr 2027
- Lead sponsor
- Duke University
- Diseases
- Stroke
- NCT number
- NCT06765642
What you commit to
- Study type: Interventional
- Planned participants: 26
- From 9 Jun 2025 to the primary completion date, 13 Apr 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Presence of any MRI/rTMS risk factors including but not limited to:
- an electrically, magnetically, or mechanically activated metallic or nonmetallic implant including cardiac pacemaker, intracerebral vascular clips or any other electrically sensitive support system.
- a non-fixed metallic part in any part of the body, including a previous metallic injury to the eye.
- history of seizure disorder before stroke or seizure after stroke.
- preexisting scalp lesion or bone defect or hemicraniectomy.
- Concurrent enrollment in another interventional stroke recovery study.
Other illness
- Other co-existent neuromuscular disorders affecting upper extremity motor impairment.
- History of medically uncontrolled depression or other neuropsychiatric disorders despite medications either before or after a stroke that may affect the subject's ability to participate in the study.
- Uncontrolled hypertension despite medical treatment(s) at the time of randomization, defined as SBP≥185 mmHg or DBP≥110 mmHg (patient can be treated, reassessed and randomized later).
Other
- Bilateral strokes (infarcts and/or hematoma)
- Concerns that the subject cannot comply with study procedures and visits.
- Pregnant individuals
Who the study is looking for
- Age \>=21 years old of any race or gender
- First-ever ischemic or hemorrhagic stroke (neuroimaging verified) at least 3 months from stroke onset
- Unilateral arm weakness measured by FM-UM scale \<= 62 out of 66
- Inducible rest motor threshold and testing motor threshold recorded from the affected first dorsal interosseous (FDI) muscle from the study subject
Age in the registry: 21 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Duke University Medical Center Coordinator of this site? Confirm its status | Durham | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.