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NCT06768528Active, not recruiting

Association Between GalectiN-3 and pOSt-operative atrIal Fibrillation After Coronary Artery bypaSs Graft

Source: ClinicalTrials.gov · Last updated 11 Sept 2026

Brief summary (registry, in English)

The goal of this observational study is to test the association between high levels of Galectin-3 and the occurrence of post-operative atrial fibrillation after isolated coronary artery bypass grafting (CABG). The main question\[s\] it aims to answer are: * Is Galectin-3 an accurate biomarker to predict higher risk of developing post-operative atrial fibrillation? * Are high levels of Galectin-3 associated to other post-operative complications and major adverse cardiovascular events? Participants will be enrolled during pre-operative evaluation and a peripheral blood sample collection will be performed in the 24h before CABG. Participants will then be followed for a period of 12 months (daily during hospitalization and 3 appointments after hospital discharge) to determine whether patients with higher levels of Galectin-3 will have worse outcomes.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
90 (estimated)
First submitted
20 Dec 2022
Start date
1 Jan 2023
Primary completion date
27 Jan 2026
Lead sponsor
University of Sao Paulo General Hospital
NCT number
NCT06768528

What you commit to

  • Study type: Observational
  • Planned participants: 90
  • From 1 Jan 2023 to the primary completion date, 27 Jan 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Renal dysfunction with estimated glomerular filtration rate less than 30ml / min / 1.73m² or dialysis therapy
  • Patients with previous atrial fibrillation
  • Concomitant valve surgery

Lab values

  • Moderate to severe left ventricular dysfunction (ejection fraction \< 40%)

Other

  • Inability to sign the free and informed consent form
  • Pregnancy

Who the study is looking for

  • Patients undergoing coronary artery bypass graft surgery

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Instituto do Coração - Hospital das Clínicas - Faculdade de Medicina da Universidade de São Paulo
Coordinator of this site? Confirm its status
São PauloBrazilUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.