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NCT06771960Recruiting

Association Between RVT and Prognosis After Neoadjuvant Targeted Therapy in EGFR NSCLC

Association Between Residual Viable Tumor and Prognosis After Neoadjuvant Targeted Therapy in EGFR-Mutated Non-small Cell Lung Cancer

Source: ClinicalTrials.gov · Last updated 21 Feb 2025 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

EGFR-mutated NSCLC is a distinct subtype that responds well to targeted therapies. Neoadjuvant targeted therapy aims to downstage tumors and improve surgical outcomes, but the prognostic role of residual viable tumor (RVT) remains unclear. This retrospective study examines the association between RVT and survival outcomes. The findings will further validate the importance of RVT as a surrogate.

Status (registry)
Recruiting
Study type
Observational
Enrollment
120 (estimated)
First submitted
8 Jan 2025
Start date
1 Feb 2025
Primary completion date
1 Dec 2025
Lead sponsor
Guangdong Provincial People's Hospital
Diseases
Lung cancer
NCT number
NCT06771960

What you commit to

  • Study type: Observational
  • Planned participants: 120
  • From 1 Feb 2025 to the primary completion date, 1 Dec 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • A history of prior chemotherapy, immunotherapy, or radiotherapy.

Other illness

  • A history of malignancy or lung surgery;

Other

  • Missing key data.

Who the study is looking for

  • Age 18-80 years old;
  • Pathologically diagnosed EGFR-mutated non-small cell lung cancer (NSCLC);
  • Treated with neoadjuvant targeted therapy;
  • Undergoing definitive surgery.

Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Guangdong Provincial People's Hospital
Coordinator of this site? Confirm its status
GuangzhouChinaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.