NCT06773299Active, not recruiting
Enhancing Intergenerational Health in Nigeria: Peripartum as Critical Life Stage for Cardiovascular Health
Source: ClinicalTrials.gov · Last updated 24 Jul 2026
Brief summary (registry, in English)
The purpose of the ENHANCE-CVH study is to promote intergenerational cardiovascular health (CVH) of women and children in Abuja and the surrounding Federal Capital Territory of Nigeria. The study team plans to achieve this through an adaptation of an existing evidence based intervention - Parents as Teachers (PAT) curriculum + Healthy Eating Active Living Taught at Home (HEALTH) - among pregnant women with obesity and their children in Nigeria. The aim of the study is to evaluate the effectiveness and implementation of community health educator-led delivery of the PAT+HEALTH intervention via home visits to answer the following main questions: * Will the women participating in the intervention have a greater change in weight from baseline to 18-month follow up compared to the women who do not? * Will the women and children in the intervention group display better CVH promoting lifestyle behaviors compared to those in the control group? Participants in the study will complete baseline surveys and have clinical data, lab data, and body measurements captured. Participants will also have these procedures repeated at birth and every 6 months up to 24 months post-delivery. Once randomized to the intervention group, participants will complete 40 biweekly PAT+HEALTH curriculum delivery sessions, each lasting approximately 60-90 minutes.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 1000 (estimated)
- First submitted
- 16 Dec 2024
- Start date
- 23 Jun 2025
- Primary completion date
- Oct 2027
- Lead sponsor
- Washington University School of Medicine
- Diseases
- Obesity, High blood pressure
- NCT number
- NCT06773299
What you commit to
- Study type: Interventional
- Planned participants: 1000
- From 23 Jun 2025 to the primary completion date, Oct 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Treatment with medications known to impact weight (e.g., corticosteroids, antipsychotics),
Other
- Current enrollment in a weight loss program,
- Inability to engage in a walking program,
- Active substance abuse
- Plan to relocate within the next 2 years, or
- Unwilling to provide informed consent.
Who the study is looking for
- •≥18 years of age,
- Pregnant women under 14 weeks gestation,
- Singleton gestation,
- Body mass index \> 30 kg/m2
- Willing to participate in ENHANCE CVH for 2 years,
- Planning to receive prenatal care and deliver at either one of the participating primary healthcare, centers or University of Abuja Teaching Hospital, and
- Able to give informed consent for study participation, understanding she and her child will both be involved.
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Abuja Teaching Hospital Coordinator of this site? Confirm its status | Abuja | Nigeria | Unknown status |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.