NCT06776289Not yet recruitingPhase 4
Endodontic Microsurgery
Endodontic Microsurgery With and Without Platelet-Rich Fibrin
Source: ClinicalTrials.gov · Last updated 29 Jul 2026
Brief summary (registry, in English)
Current literature on platelet rich fibrin (PRF) use in apicoectomies, also known as endodontic microsurgery, is sparse. PRF use in oral surgery or periodontal surgery has been more thoroughly researched. Whether it is able to reduce post-op pain or if it improves success rate in endodontic microsurgery is not well known. It is also not well known if it will be able to increase the rate of healing. This study will evaluate the success of endodontic microsurgery with and without PRF.
- Status (registry)
- Not yet recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 9 Jan 2025
- Start date
- Oct 2026
- Primary completion date
- Feb 2027
- Lead sponsor
- Mark Schachman
- NCT number
- NCT06776289
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 20
- From Oct 2026 to the primary completion date, Feb 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Systematic disease contraindicating surgery
Other
- Patients with vertical root fractures
- Patients with non-restorable teeth
- Patients with class 3 mobility
- Pregnant
- Smoker
Who the study is looking for
- Maxillary or Mandibular Anterior teeth and premolars #4-13 and #20-29 with a history of failing RCT and a periapical radiolucency will be accepted
Age in the registry: 18 years to 90 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Kentucky College of Dentistry Endodontics Division Coordinator of this site? Confirm its status | Lexington | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.