NCT06776978Completed
Effectiveness of TDCS Over Broca's Area in Verb Naming: a Randomized, Double-Blind, Crossover Study
La Stimolazione Transcranica (tDCS) E Transpinale a Corrente Diretta (tsDCS) Per Il Recupero Delle Funzioni Cognitive in Soggetti Affetti Da Patologia Cerebrovascolare O Neurodegenerativa
Source: ClinicalTrials.gov · Last updated 15 Jan 2025
Brief summary (registry, in English)
This clinical trial investigated whether transcranial direct current stimulation (tDCS) over Broca's area (F5) could improve verb naming abilities in adults with aphasia. Additionally, the study evaluated the stability of the treatment response to tDCS over time. The main questions this study sought to answer were: * Does tDCS improve verb naming abilities compared to inactive (sham) stimulation? * Are the observed effects stable over time? Participants received 10 daily sessions of tDCS over two consecutive weeks (5 days per week). The study included two treatment conditions, separated by one-month washout period: * Active tDCS: Stimulation over Broca's area at 2 mA; * Sham tDCS: Stimulation mimicking the active condition without delivering electrical current. During the treatment, participants were asked to name aloud videos of actions displayed on a computer screen. One month after each treatment condition, follow-up testing was conducted to evaluate the stability of the treatment response.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 32 (actual)
- First submitted
- 10 Jan 2025
- Start date
- 4 Dec 2023
- Primary completion date
- 13 Dec 2024
- Lead sponsor
- I.R.C.C.S. Fondazione Santa Lucia
- Diseases
- Stroke
- NCT number
- NCT06776978
What you commit to
- Study type: Interventional
- Participants enrolled: 32
- From 4 Dec 2023 to the primary completion date, 13 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- acute or chronic neurological symptoms requiring medication;
Other
- attention and/or memory deficits.
Who the study is looking for
- native Italian proficiency;
- pre-morbid right-handedness;
- a single left hemispheric stroke at least 6 months before the investigation.
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| I.R.C.C.S. Fondazione Santa Lucia Coordinator of this site? Confirm its status | Roma | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.