NCT06780995Recruiting
Power Exercise for Stroke Recovery: The POWER Pilot Trial (POWER-P)
Power Exercise for Stroke Recovery: A Pilot Randomized Controlled Trial (POWER-Pilot)
Source: ClinicalTrials.gov · Last updated 23 Dec 2025
Brief summary (registry, in English)
Weakness is one of the most common consequences of stroke. For the over 750,000 Canadians living with stroke, many daily activities like standing from a chair, walking and balance not only require strength but often efforts in bursts, known as muscle power. Strength training can improve muscle strength and, when performed at higher speeds, can help build muscle power. Current guidelines for stroke recommend strength training but these are commonly performed at lower intensities and do not include any focus on building muscle power. There has been very little research on power training after stroke. A 10-week power training program for people living with stroke, Power Exercise for Stroke Recovery (POWER-Feasibility, NCT05816811) was recently evaluated. POWER includes 3 phases of progressive exercise: building familiarity with the upper and lower body exercises, then strength, and lastly muscle power. The results from POWER-Feasibility are promising, suggesting that POWER is safe and may improve stroke recovery. POWER-Feasibility was a small study (15 participants), and POWER was not compared to a control intervention. A pilot randomized controlled trial of POWER (POWER-Pilot) will now be conducted. Sixty people who are at least 6 months after stroke will be recruited. They will be randomly assigned to participate in POWER or standard strength training for stroke at lower intensities and without focus on power training. The feasibility of a randomized study will be examined, and whether POWER can improve walking, strength and balance compared to the control group. Results from POWER-Pilot will help design a larger randomized trial in the future (POWER-RCT), and may ultimately be important for stroke rehabilitation teams to better understand whether power training can help people recovering from stroke.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 9 Dec 2024
- Start date
- 15 Sept 2025
- Primary completion date
- 28 Feb 2027
- Lead sponsor
- McMaster University
- Diseases
- Stroke
- NCT number
- NCT06780995
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 15 Sept 2025 to the primary completion date, 28 Feb 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Any contraindications to exercise for people with cardiovascular disease, such as unstable angina, uncontrolled hypertension, orthostatic blood pressure with exercise, or uncontrolled arrhythmias or
- Actively engaged in or have made plans to engage in stroke rehabilitation services
Who the study is looking for
- ≥19 years old
- ≥6 months poststroke,
- able to walk \>10 meters with or without an assistive device
- have mild to moderate stroke severity (modified Rankin Scale ≤3)
- without significant cognitive impairment that would preclude safe exercise, screened via Montreal Cognitive Assessment-Blind score \<18
Age in the registry: 19 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| McMaster University Coordinator of this site? Confirm its status | Hamilton | Canada | Recruiting |
| The University of British Columbia - Okanagan Campus Coordinator of this site? Confirm its status | Kelowna | Canada | Recruiting |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.