NCT06785168Completed
Effects of Resistance Training on Sarcopenia in Older Patients With Chronic Heart Failure
Effects of Resistance Training on Sarcopenia in Older Patients With Chronic Heart Failure: A Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 6 Aug 2026
Brief summary (registry, in English)
The goal of study is to evaluate the effects of an eight-week machine-based resistance training program on managing sarcopenia in older outpatients with chronic heart failure (HF) at Military Hospital 175.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 146 (actual)
- First submitted
- 31 Dec 2024
- Start date
- 27 Jan 2025
- Primary completion date
- 4 Aug 2026
- Lead sponsor
- Kieu Dang Phuong Nguyen
- Diseases
- Heart failure
- NCT number
- NCT06785168
What you commit to
- Study type: Interventional
- Participants enrolled: 146
- From 27 Jan 2025 to the primary completion date, 4 Aug 2026
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Early stage after acute coronary syndrome (within the first 2 days)
- Unstable coronary artery disease
- Decompensated heart failure
- Acute venous thrombosis or recent arterial embolism (pulmonary or systemic)
- Acute systemic disease or fever
- Uncontrolled or life-threatening atrial or ventricular arrhythmias (including new-onset atrial fibrillation or flutter)
- Uncontrolled tachycardia (resting heart rate \> 120 beats per minute)
- Uncontrolled diabetes
- Significant myocardial ischemia at low workloads \< 2 METs or 50W
- NYHA IV heart failure
- Complex ventricular arrhythmias at rest or with exertion
- Resting heart rate ≥ 100 bpm when lying down
Other
- Acute myocarditis, pericarditis, endocarditis
- Aortic dissection of the valve
- Severe symptomatic aortic stenosis
- Third-degree AV block
- Symptomatic orthostatic hypotension (\> 20 mmHg)
- Gradually increasing fatigue during exercise or dyspnea at rest or with exertion within the past 3-5 days
- Relative contraindications according to ACSM 2022:
- Weight gain ≥ 1.8 kg in the past 1-3 days
- Simultaneous use of continuous or intermittent Dobutamine
- Decrease in blood pressure with exercise
- Comorbidities that limit exercise
- Severe obstructive hypertrophic cardiomyopathy
- Have participated in a cardiovascular rehabilitation program within the last 6 months
- Do not agree to participate in the study
Who the study is looking for
- Aged ≥ 60 years old
- Meet the diagnostic criteria of 2019 AWGS2 sarcopenia, can be diagnosed once meeting (1) + (2) or (1) + (3) or (1) + (2) + (3): (1) Appendicular skeletal muscle mass (ASM): dual-energy X-ray absorptiometry (DXA) (male \<7.0 kg/m², female \<5.4 kg/m²). (2) Muscle strength: handgrip strength (male \<28.0 kg, female \<18.0 kg). (3) Physical performance: 6-meter walking speed \<1.0 m/s.
- Meet the diagnostic criteria of heart failure following ESC 2021.
- Clearly understand the content and purpose of the study and sign the informed consent form.
Age in the registry: 60 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Military Hospital 175 Coordinator of this site? Confirm its status | Ho Chi Minh City | Vietnam | Unknown status |
| University of Medicine and Pharmacy at Ho Chi Minh City Coordinator of this site? Confirm its status | Ho Chi Minh City | Vietnam | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.