NCT06786650Active, not recruitingPhase 4
Comparision of the Analgesic Effects of Intravenous Ibuprofen and Tenoxicam in Acute Migraine Attack
Source: ClinicalTrials.gov · Last updated 26 Jun 2025
Brief summary (registry, in English)
The aim of this clinical trial is to compare the efficacy of two different non-steroidal anti-inflammatory analgesic drugs in the palliation of headache in acute migraine attack. The main questions it aims to answer are: 1. Is there a difference between the efficacy of two different nonsteroidal anti-inflammatory analgesics? 2. Is there a significant difference between the side effects of two different nonsteroidal anti-inflammatory drugs? Researchers will compare intravenous tenoxicam to intravenous ibuprofen to see if tenoxicam works to treat migraine attack. Treatments will; 1. be administered in 100 cc saline to ensure blinding in the group. 2. Randomisation will be done by closed envelope method. 3. Numerical Pain Scale (NRS) will be used to evaluate the analgesic efficacy of the drugs. NRS scores will be recorded in both groups before starting treatment (baseline) and at 30, 60 and 120 minutes after treatment. 4. Any side effects due to medication will be recorded.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 29 Nov 2024
- Start date
- 15 May 2024
- Primary completion date
- 15 Oct 2024
- Lead sponsor
- Haydarpasa Numune Training and Research Hospital
- Diseases
- Migraine
- NCT number
- NCT06786650
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 100
- From 15 May 2024 to the primary completion date, 15 Oct 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Being admitted with an acute migraine attack and having used medication for migraine treatment within 12 hours before admission.
Other illness
- Having a history of allergy to any of the drugs to be used in the study.
- Having a history of comorbidities for which the drugs to be used in the study are contraindicated.
Age
- Being under 18 years of age.
Other
- Being pregnant or breastfeeding.
- Being admitted to the emergency department with headache due to causes other than migraine (secondary).
Who the study is looking for
- Being between the ages of 18-65.
- Having a known diagnosis of migraine.
- Exclusion of secondary causes to explain the headache in the emergency department.
- Having migraine during a migraine attack and not having received any medical treatment for migraine before the application.
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Haydarpasa Numune Training and Research Hospital Coordinator of this site? Confirm its status | Istanbul | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.