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NCT06787534Completed

The Favorable Impact of HBcAb Positive Grafts on Liver Transplantation for HBV-related HCC

The Favorable Impact of Hepatitis B Core Antibody Positive Grafts on Liver Transplantation for Hepatitis B Virus-related Hepatocellular Carcinoma: a Nationwide Multicenter Retrospective Cohort Study

Source: ClinicalTrials.gov · Last updated 22 Jan 2025

Brief summary (registry, in English)

The utilization of marginal grafts may help alleviate the demand mismatch. However, strategies to optimize the use of hepatitis B core antibody (HBcAb) positive grafts still requires further investigation. This study aims to investigate possible interactions between HBcAb positive grafts, HCC and HBV-related diseases, and long-term patient and graft survival. The study retrospectively analyzed patients undergoing liver transplantation in 8 centers between January 2015 and December 2020.

Status (registry)
Completed
Study type
Observational
Enrollment
6924 (actual)
First submitted
14 Jan 2025
Start date
1 Jan 2015
Primary completion date
1 Jun 2015
Lead sponsor
Xiao Xu
NCT number
NCT06787534

What you commit to

  • Study type: Observational
  • Participants enrolled: 6924
  • From 1 Jan 2015 to the primary completion date, 1 Jun 2015
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • (1) re-transplantation, combined organ transplantation or living donor liver transplantation; (2) intrahepatic cholangiocarcinoma or combined hepatocellular-cholangiocarcinoma; (3) HBsAg positive graft; and (4) missing of baseline data. Patients who were lost to follow-up were also excluded.

Who the study is looking for

  • (1) primary transplantation; (2) complete baseline data.

Age in the registry: 18 years to - · Sex: All

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.