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NCT06790173Enrolling by invitation

Effects of Strategy Training for Physical Activity (STPA) on the Post-stroke Executive Dysfunction

Effects of Strategy Training for Physical Activity on Executive Functions in Stroke Survivors With Cognitive Impairments: a Phase II Randomized Controlled Trial

Source: ClinicalTrials.gov · Last updated 11 Apr 2025 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

The goal of this randomized controlled trial is to examine if combining strategy training and physical activity (STPA) works to improve executive function in community-dwelling adults with post-stroke cognitive impairment. The main questions it aims to answer are: * Does STPA and physical exercise alone lead to greater improvements in executive function among stroke survivors relative to the control intervention with education? * Does STPA outperform physical exercise alone in the efficacy of executive functions? * Do the effects of STPA on executive functions transfer to the global cognition, balance, and activity-participation outcomes? * Do the effects of STPA persist for at least 6 months post-intervention? Researchers will compare the efficacy of the STPA intervention against physical exercise alone or control intervention with education. Participants will: receive STPA, physical activity only, or an education program 2 to 3 sessions per week until finishing 12 sessions. be assessed clinical outcomes at 5 times: pre-intervention, post-intervention, 3-month, 6-month, and 12-month follow-up.

Status (registry)
Enrolling by invitation
Study type
Interventional
Enrollment
120 (estimated)
First submitted
17 Jan 2025
Start date
3 Feb 2025
Primary completion date
1 Jun 2029
Lead sponsor
Taipei Medical University
Diseases
Stroke
NCT number
NCT06790173

What you commit to

  • Study type: Interventional
  • Planned participants: 120
  • From 3 Feb 2025 to the primary completion date, 1 Jun 2029
  • 5 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study design.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Any conditions that may impede the participation in the study, such as severe aphasia, postoperative immobilization, or major neuropsychiatric diseases.
  • Pre-stroke mRS \>1

Other

  • Modified Rankin Scale (mRS) = 5
  • 6-level Saltin-Grimby Physical Activity Level Scale (SGPALS) = 5 or 6
  • Participating in other interventional study concurrently

Who the study is looking for

  • 18 to 80 years old
  • A diagnosis of stroke within the past 3 year
  • Speaking Mandarin
  • Montreal Cognitive Assessment (maximum=30) \< 26
  • 14 item-Executive Interview \> 3
  • Willing to provide informed consent

Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (5)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
Taipei Medical University - Shuang Ho Hospital, Ministry of Health and Welfare
Coordinator of this site? Confirm its status
New Taipei CityTaiwanUnknown status
Taipei Tzu Chi Hospital
Coordinator of this site? Confirm its status
New Taipei CityTaiwanUnknown status
Taipei Municipal Wanfang Hospital
Coordinator of this site? Confirm its status
TaipeiTaiwanUnknown status
Taipei Medical University Hospital
Coordinator of this site? Confirm its status
TaipeiTaiwanUnknown status
National Taiwan University Hospital
Coordinator of this site? Confirm its status
TaipeiTaiwanUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.