NCT06791239Completed
Comparison of Thoracic Squeeze and Manual Diaphragmatic Release Technique in COPD Patients
Comparison of Thoracic Squeeze and Manual Diaphragmatic Release Technique on Respiratory Parameters and Functional Capacity in COPD Patients
Source: ClinicalTrials.gov · Last updated 22 Aug 2025
Brief summary (registry, in English)
The goal of this randomized control trial is to evaluate and compare the efficacy of two physiotherapy techniques-Thoracic Squeeze Technique (TST) and Manual Diaphragmatic Release Technique (MDRT)-on improving respiratory parameters, functional capacity, and quality of life in patients with mild to moderate Chronic Obstructive Pulmonary Disease (COPD). Objectives: * Assess the impact of TST and MDRT on respiratory parameters (FEV1, FVC, FEV1/FVC ratio, and chest expansion). * Compare the functional capacity outcomes of the two techniques using the 6-Minute Walk Test (6MWT). * Evaluate the effects of TST and MDRT on patient wellbeing and daily life through the COPD Assessment Test (CAT). Study Design: The study involves 34 participants, divided into two groups (n=17 each) via sealed envelope randomization. Both groups will receive their respective interventions (TST or MDRT) alongside a standardized pulmonary rehabilitation protocol (pursed-lip breathing, diaphragmatic breathing, active cycle of breathing, and endurance exercises). The intervention will be conducted three times per week for three weeks. Outcome Measures: Primary outcomes include respiratory parameters assessed through spirometry and chest expansion using a measuring tape. Secondary outcomes include functional capacity (6MWT) and patient wellbeing (CAT scores). Baseline and post-intervention measures will be analyzed using SPSS, employing Mixed ANOVA to determine interaction effects.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 36 (actual)
- First submitted
- 14 Jan 2025
- Start date
- 1 Feb 2025
- Primary completion date
- 30 May 2025
- Lead sponsor
- Riphah International University
- Diseases
- COPD
- NCT number
- NCT06791239
What you commit to
- Study type: Interventional
- Participants enrolled: 36
- From 1 Feb 2025 to the primary completion date, 30 May 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients who have undergone recent 6 to 12 weeks cardio thoracic or abdominal surgery.
Other illness
- Patients who have a recent history of chest wall or abdominal trauma; substantial chest wall deformity History of recent fractures and cognitive impairments.
Other
- Patients with unstable hemodynamic parameters (arterial pressure \<100mmHg Systolic and \<60 mmHg diastolic blood pressure.
Who the study is looking for
- Patients with mild or moderate COPD according to the GOLD criteria.GOLD 1: Mild FEV1 ≥ 80% predicted value, GOLD 2: Moderate FEV1 between 50% and 80% predicted value.
- Age between 40- 60 years.
- Both male and female.
- Patients who are willing to give voluntary consent to practice.
Age in the registry: 40 years to 60 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Lady Reading Hospital Coordinator of this site? Confirm its status | Peshawar | Pakistan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.