NCT06791941Recruiting
Study of the Contribution of Mutant p53/YAP Proteins to Therapy Resistance in Recurrent Head and Neck Cancer
Source: ClinicalTrials.gov · Last updated 24 Jan 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Multicenter, non-interventional, retrospective/prospective study of a biological nature, on patients affected by head and neck tumors, for which the collection and use of tissue samples is planned for the study of the mutational profile, the transcriptional profile and the proteomic profile.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 18 (estimated)
- First submitted
- 16 Jan 2025
- Start date
- 7 Mar 2024
- Primary completion date
- 7 Mar 2029
- Lead sponsor
- Regina Elena Cancer Institute
- Diseases
- Head and neck cancer
- NCT number
- NCT06791941
What you commit to
- Study type: Observational
- Planned participants: 18
- From 7 Mar 2024 to the primary completion date, 7 Mar 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous head and neck cancer
Other illness
- Second cancer undergoing treatment or follow-up for less than 5 years
Other
- Presence of distant metastases at the time of diagnosis
Who the study is looking for
- Age over 18
- Patients with squamous cell tumors of the oral cavity, pharynx or larynx
- Surgical patients with primary HNSCC tumors, who have not had previous tumors in other sites or adjuvant treatments prior to surgery.
- Availability of adequate material (tissue) for the planned analyses
- Availability of follow-up data for at least one year (retrospective part)
- Written informed consent (prospective part and/or, for the retrospective part, traceable patients and/or patients in follow-up and/or if necessary for the legal nature/institutional purposes of the participating centers).
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| IRCCS National Cancer institute Coordinator of this site? Confirm its status | Roma | Italy | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.