NCT06791967Completed
The Impact of a Home-Based Walking Exercise Program on Heart Failure
Effectiveness of a Home-base Walking Exercise Program on Depression,Frailty,and Quality of Life in Patients With Heart Failure: A Single-Center Randomized-Controlled Trial
Source: ClinicalTrials.gov · Last updated 12 May 2026
Brief summary (registry, in English)
Heart disease is the second leading cause of death in Taiwan, with approximately 700,000 individuals affected by heart failure. Despite the proven benefits of rehabilitative exercise, participation in cardiac rehabilitation remains suboptimal. To address this, integrating physical activity into daily life, such as home-based walking exercises, offers a practical alternative to promote health and improve outcomes in heart failure patients. Walking exercises have been shown to significantly impact mortality rates and enhance the quality of life in this population. This study aims to assess the effects of a 12-week home-based walking exercise program on depression, frailty, and quality of life in patients with heart failure. Using an experimental design, heart failure patients hospitalized in a medical center's internal medicine ward were randomly divided into an experimental group (n=34) and a control group (n=34). While both groups received standard health education, the experimental group also participated in a home-based walking intervention after discharge. Data were collected before the intervention and at the 1st and 3rd months post-intervention. The generalized estimation equation (GEE) was employed to analyze changes in depression, frailty, and quality of life, focusing on group differences and interactions between time and group. The expected outcomes of the study include improved quality of life, reduced frailty, and alleviated depression in the experimental group, highlighting the value of home-based walking exercise. Additionally, the intervention model can complement existing post-discharge nursing practices by incorporating remote nursing guidance to enhance exercise adherence without increasing healthcare costs. This approach not only benefits patients by encouraging long-term physical activity but also reduces the burden on healthcare systems, making it a sustainable and effective strategy for managing heart failure.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 68 (actual)
- First submitted
- 12 Jan 2025
- Start date
- 2 Mar 2025
- Primary completion date
- 25 Jul 2025
- Lead sponsor
- National Taiwan University Hospital
- Diseases
- Heart failure
- NCT number
- NCT06791967
What you commit to
- Study type: Interventional
- Participants enrolled: 68
- From 2 Mar 2025 to the primary completion date, 25 Jul 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients diagnosed with heart failure classified as New York Heart Association (NYHA) functional class IV by a physician.
- Patients with cognitive impairment or language communication disorders.
Other
- Patients diagnosed with depression by a psychiatrist.
- Patients who are bedridden for an extended period.
Who the study is looking for
- Patients diagnosed with heart failure classified as New York Heart Association (NYHA) Functional Class II-III by a physician.
- Approval from the attending physician to participate in the home-based walking program after discharge.
- Aged between 18 and 80 years.
- Patients unable to attend outpatient cardiac rehabilitation.
- No regular exercise habits, such as performing less than 30 minutes of aerobic exercise per week.
- Able to walk independently without the aid of assistive devices.
- Patients with clear consciousness, no cognitive impairment, and no history of mental illness.
- Able to communicate in Mandarin or Taiwanese dialect.
- Willing to participate in the study, sign the informed consent form, and comply with the home-based walking program.
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| National Taiwan University Hospital Coordinator of this site? Confirm its status | Taipei | Taiwan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.