NCT06794359Enrolling by invitation
Minimally Invasive Coronary Artery Bypass Surgery in Patients With Multi Vessel Coronary Disease
Minimally Invasive Coronary Artery Bypass Surgery: Prospective and Randomized Study to Validate the Minimally Invasive Approach Through Left Anterior Mini Thoracotomy in Patients With Milti Vessel Coronary Disease
Source: ClinicalTrials.gov · Last updated 4 May 2026
Brief summary (registry, in English)
The objective of this study is to evaluate the safety and feasibility of Minimally Invasive Coronary Artery Bypass surgery in selected patients ,with multi vessel coronary disease. This trial is designed to be a pilot study that will gather comparative information on the clinical performance of the minimally invasive treatment, evaluated by the composite measure of all-cause death, myocardial infarction, stroke, or unplanned repeat revascularization - in hospital, 30-day and 6 months.
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 14 Oct 2024
- Start date
- 1 Oct 2023
- Primary completion date
- 1 Jul 2026
- Lead sponsor
- University of Sao Paulo General Hospital
- Diseases
- Coronary artery disease
- NCT number
- NCT06794359
What you commit to
- Study type: Interventional
- Planned participants: 100
- From 1 Oct 2023 to the primary completion date, 1 Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Need for any concomitant cardiac surgery other than CABG (e.g. valve surgery, aortic repair, etc.), or intent that if the patient randomizes to surgery, any cardiac surgical procedure other than isolated CABG will be performed
- Emergency surgery
Other illness
- Chronic Pulmonary obstructive disease
- Renal failure disease
- Peripheral vascular disease
- Non cardiac co-morbidities with life expectancy less than 1 year
Other
- Reoperation
- Left ventricle disfunction (EF\<40%)
- Obesity
- Sternum anatomic defects including pectus excavatum
- Ascending aorta severe calcification
Who the study is looking for
- Patients 18-years-old or older
- Isolated myocardial revascularization procedure
- Double or Triple-vessel disease with proximal or mid LAD disease with angiographic diameter stenosis \> 70% by visual analysis in all territories, requiring myocardial revascularization OR proximal LAD disease with angiographic diameter stenosis 50-70% by visual analysis in any territory but with invasive or non-invasive evidence of flow-limiting stenosis in all three territories, requiring myocardial revascularization
- Total SYNTAX score \> 22 or low Syntax score unsuitable for PCI
- Clinical and anatomic eligibility for both Minimally invasive and Conventional CABG surgery as agreed to by surgical team.
- Silent ischemia, stable angina, unstable angina or recent MI
- If recent MI, cardiac biomarkers must have returned to normal prior to randomization
- Ability to sign informed consent and comply with all study procedures
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| INCOR - Heart Institute from the University of Sao Paulo Coordinator of this site? Confirm its status | São Paulo | Brazil | Unknown status |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.