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NCT06795360Not yet recruiting

Weight Changes After Incretin-mimetics

Source: ClinicalTrials.gov · Last updated 24 Feb 2026

Brief summary (registry, in English)

The goal of this study is to identify people at risk of weight regain after stopping an injectable weight loss drug. The main question the investigators aim to answer is: Can weight regain be predicted by measuring circulating Agouti-related peptide, a small protein coming from the brain?

Status (registry)
Not yet recruiting
Study type
Interventional
Enrollment
52 (estimated)
First submitted
22 Jan 2025
Start date
1 Dec 2026
Primary completion date
30 Nov 2031
Lead sponsor
Medical College of Wisconsin
Diseases
Obesity
NCT number
NCT06795360

What you commit to

  • Study type: Interventional
  • Planned participants: 52
  • From 1 Dec 2026 to the primary completion date, 30 Nov 2031
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • patients taking steroid medications
  • post solid organ or bone marrow transplant
  • current recreational drug use

Other illness

  • type 1 or type 2 diabetes
  • heart disease
  • advanced kidney disease (CKD stage 4 and 5)
  • decompensated liver disease
  • active cancer
  • HIV/AIDS

Other

  • weight \> or = 400 lb
  • anemia
  • hyperthyroidism
  • untreated hypothyroidism
  • pregnancy/plan for pregnancy in the next 6 months
  • breastfeeding
  • post-menopausal women
  • current smoker
  • night shift or rotating shift workers

Who the study is looking for

  • adults 18 years or older
  • men and women
  • prescribed an incretin-mimetic for weight loss and for whom insurance coverage for this specific drug will lapse
  • any ethnicity

Age in the registry: 18 years to 50 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.