NCT06795867Recruiting
Acceptance and Commitment Therapy to Improve Disability in Chronic Migraine
Does Acceptance and Commitment Therapy (ACT) Improve Disability in Chronic Migraine? A Randomized Headache Center Trial
Source: ClinicalTrials.gov · Last updated 31 Oct 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The goal of this clinical trial is to learn if the behavioral treatment called Acceptance and Commitment Therapy (ACT) works to improve disability in adults with chronic migraine. The main questions it aims to answer are: Does the use of ACT added to usual treatment improve scores on questionnaires designed to measure daily functioning and activity? Does the use of ACT added to usual treatment improve scores on diaries designed to measure headache frequency and pain? Researchers will compare adding ACT to usual headache treatments to usual headache treatments without ACT. Participants who are selected for ACT will take 8 classes to learn ACT and then will practice it at home, in addition to their regular headache treatment. Those not selected will continue their regular headache treatment. Four times over the following year, participants will answer questions about their symptoms during each of four virtual visits. They will also keep a daily headache diary during the study
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 14 Jan 2025
- Start date
- 21 Apr 2025
- Primary completion date
- Dec 2027
- Lead sponsor
- Brigham and Women's Hospital
- Diseases
- Migraine
- NCT number
- NCT06795867
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 21 Apr 2025 to the primary completion date, Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Psychotherapy in the prior 18 months
- Any previous experience with mindfulness or meditation approaches
Other illness
- Known major depression or other psychiatric condition
Other
- Non-English speaking
- Secondary headache diagnosis
- Any reason the provider feels would limit participant ability to learn or practice ACT
Who the study is looking for
- Willingness and ability to engage in the consent process
- Willingness to participate in the study, despite randomization outcome
- Availability for the duration of the study
- Diagnosis of chronic migraine followed at the Graham Headache Center
- Access to the necessary resources for participating in a technology-based intervention
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Brigham and Women's Faulkner Hospital Coordinator of this site? Confirm its status | Boston | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.