NCT06797661Recruiting
Insights Into the Pathophysiology of Neurovascular Uncoupling in Patients With Brain Lesions.
Source: ClinicalTrials.gov · Last updated 14 Sept 2026
Brief summary (registry, in English)
Neurovascular uncoupling (NVU) represents a major source of potential bias for the identification of eloquent brain regions through activation procedures in blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI). Same region shows proper pattern in glucose metabolism in victiny of brain lesions, investigated with positron emitted tomography with radiolabeled glucose (PET-FDG) This research project aims at investigating the mechanisms of NVU by using a multimodal noninvasive imaging approach in neurosurgical patients.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 23 Jan 2025
- Start date
- 17 Feb 2025
- Primary completion date
- 13 Sept 2026
- Lead sponsor
- Erasme University Hospital
- Diseases
- Glioblastoma
- NCT number
- NCT06797661
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 17 Feb 2025 to the primary completion date, 13 Sept 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- previous brain surgery
- Previous adverse reaction to gadovist (contrast agent)
Other illness
- respiratory failure
- Diabetes (type I and II)
Other
- Asthma
- Claustrophobia
- Pregnancy and Breath feeding
Who the study is looking for
- patients in the study include prior imaging showing a potentially resectable intra-cerebral mass lesion. Patient has to be included before surgery, chemotherapy and radiation
Age in the registry: 18 years to 90 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| HUB-Erasme Hospital Coordinator of this site? Confirm its status | Brussels | Belgium | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.