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NCT06798805Active, not recruiting

Unraveling the Role of Extracellular Vesicles-driven Senescence in Myeloproliferative Neoplasms

Source: ClinicalTrials.gov · Last updated 29 Jan 2025

Brief summary (registry, in English)

In this study the aim is to investigate the pathogenetic role of extracellular vesicles and senescence in Myeloproliferative Neoplasms. In particular, the goal of this project is to identify possible EV-based biomarkers of senescence according to gender, which are disease-specific, biology-related, and predictive of short-term outcome in terms of Event-Free Survival and to define personalized targets for new therapeutic approaches.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
110 (actual)
First submitted
30 Dec 2024
Start date
15 Feb 2022
Primary completion date
8 Aug 2024
Lead sponsor
IRCCS Azienda Ospedaliero-Universitaria di Bologna
NCT number
NCT06798805

What you commit to

  • Study type: Observational
  • Participants enrolled: 110
  • From 15 Feb 2022 to the primary completion date, 8 Aug 2024
  • 5 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • \- patients with concomitant second neoplasia

Other

  • \- Healthy Donors with neoplasia.

Who the study is looking for

  • age ≥ 18 years.
  • patients with WHO2017-defined diagnosis of Myeloproliferative Neoplasms.
  • patients at first diagnosis.
  • Informed consent signed.
  • age ≥ 18 years.
  • Informed consent signed.

Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (5)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Coordinator of this site? Confirm its status
BolognaItalyUnknown status
ASST Spedali Civili di Brescia
Coordinator of this site? Confirm its status
BresciaItalyUnknown status
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST)
Coordinator of this site? Confirm its status
MeldolaItalyUnknown status
Ospedale S. Maria Delle Croci
Coordinator of this site? Confirm its status
RavennaItalyUnknown status
Arcispedale S. Maria Nuova - IRCCS
Coordinator of this site? Confirm its status
Reggio EmiliaItalyUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.